Describe the intracellular signaling pathway that turns on inside an activated T cell
Tyrosine kinases activate Phospholipase Cg. This cleaves PIP2 to DAG and IP3. Dag and calcium activate Protein Kinase C (PKC). IP3 causes the release of calcium. The release of calcium activates the phosphatase calcineurin. PKC and calcineurin activate transcription factors NFkB and NFAT which induce the cell to divide.