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Captopril: Pharmacotherapeutics
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HTN, CHF, diabetic nephropathy, and left ventricular dysfunction
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Terms in this set (28)
Captopril: Pharmacotherapeutics
HTN, CHF, diabetic nephropathy, and left ventricular dysfunction
Captopril: Pharmacodynamics
Inhibits the ACE needed to change the inactive angiotensin I to the active form angiotensin II
Captopril: Contraindications/ Precautions
Second and third trimester of pregnancy and hypersensitivity
Captopril: Adverse Effects
Persistent nonproductive cough, angioedema, rash, hypotension, neutropenia, and dyspnea
Captopril: Lifespn/Gender/Diet
Determine pregnancy status
Assess normal dietary habits
Check BP before, during, and after therapy
Captopril Minimizing adverse effects
Monitor the patient for at least 2 hours after initial dose until blood pressure stabilizes
Assess blood reports for hyperkalemia, hyponatremia, neutropenia, and assess urine for proteinuria
Captopril: Maximizing Effects
Administer captopril at least 1 hour before meals because food decreases absorption
Captopril: Patient and Family Teaching
Teach purpose of drug therapy and any adverse reactions
Teach signs and symptoms to report
Captopril: Nursing Interventions
Monitor BP throughout therapy
BP that decreases to a normal range is indicative of successful therapy
Losartan: Pharmacotherapeutics
HTN, diabetic nephropathy, left ventricle dysfunction
Losartan: Pharmacodynamics
Selectively blocking the binding of angiotensin I to the angiotensin II receptors in many tissues
Losartan: Contraindications/Precautions
Hypersensitivity
Second and third trimester of pregnancy
Losartan: Adverse Effects
Hypotension
Diarrhea
Asthenia
Dizziness
Fatigue
Upper respiratory infection
Losartan: Lifespan/Gender/Diet
Assess pregnancy and lactation status
Assess usual lifestyle
Losartan: Max
Should be accompanied by by the recommended lifestyle changes
Avoid giving losartan with grapefruit juice