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Captopril: Pharmacotherapeutics

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Terms in this set (28)

Captopril: Pharmacotherapeutics

HTN, CHF, diabetic nephropathy, and left ventricular dysfunction

Captopril: Pharmacodynamics

Inhibits the ACE needed to change the inactive angiotensin I to the active form angiotensin II

Captopril: Contraindications/ Precautions

Second and third trimester of pregnancy and hypersensitivity

Captopril: Adverse Effects

Persistent nonproductive cough, angioedema, rash, hypotension, neutropenia, and dyspnea

Captopril: Lifespn/Gender/Diet

Determine pregnancy status
Assess normal dietary habits
Check BP before, during, and after therapy

Captopril Minimizing adverse effects

Monitor the patient for at least 2 hours after initial dose until blood pressure stabilizes
Assess blood reports for hyperkalemia, hyponatremia, neutropenia, and assess urine for proteinuria

Captopril: Maximizing Effects

Administer captopril at least 1 hour before meals because food decreases absorption

Captopril: Patient and Family Teaching

Teach purpose of drug therapy and any adverse reactions
Teach signs and symptoms to report

Captopril: Nursing Interventions

Monitor BP throughout therapy
BP that decreases to a normal range is indicative of successful therapy

Losartan: Pharmacotherapeutics

HTN, diabetic nephropathy, left ventricle dysfunction

Losartan: Pharmacodynamics

Selectively blocking the binding of angiotensin I to the angiotensin II receptors in many tissues

Losartan: Contraindications/Precautions

Hypersensitivity
Second and third trimester of pregnancy

Losartan: Adverse Effects

Hypotension
Diarrhea
Asthenia
Dizziness
Fatigue
Upper respiratory infection

Losartan: Lifespan/Gender/Diet

Assess pregnancy and lactation status
Assess usual lifestyle

Should be accompanied by by the recommended lifestyle changes
Avoid giving losartan with grapefruit juice