Upgrade to remove ads
Only $35.99/year

Pharm 3 Drugs and Therapeutic Uses

Terms in this set (53)

H. Pylori Treatment
PUD/GERD

Antibiotics + acid suppression -- usually triple, quadruple therapy (14 days)
Famotidine
PUD, GERD, Zollinger Ellison Syndrome, H pylori


OTC: heartburn, indigestion

anti- secretory agent
Omerprazole
proton pump inhibitor

PUD, GERD, Zollinger-Ellison Syndrome, H. Pylori, stress ulcer prophylaxis
Misoprostol
Prostaglandin E analog

Prevention of gastric ulcers in patients on chronic NSAIDS - not indicated for general use!!

Labor induction, pregnancy termination with mifepristone
Calcium carbonate
PUD, GERD

All OTC- heartburn and indigestion (neutralizes stomach acid)
Sucralfate
Mucosal protectant for PUD
Ondansetron
Serotonin Antagonist (1st line drug)

Suppression of N/V secondary to chemotherapy, radiation, anesthesia, pregnancy, and in some cases viral gastritis
Prochlorperazine and Promethazine
-Dopamine antagonist

Vertigo, motion sickness, PONV - post op, chemotherapy, CNS uses (schizophrenia)
Scopolamine
Anticholinergic (PRESCRIPTION)

Prevent and treat motion sickness

Used as preventative measure
Dimenthydrinate
Antihistamine

Prevent and treat motion sicknes
Loperamide
Opioid receptor agonist - OTC

Diarrhea, LOWER ileostomy volume
Diphenoxylate/Atropine
Prescription opioid for diarrhea
Psyllium preparations
Bulk forming laxative for Constipation, IBS, symptomatic MILD diarrheal relief
docusate sodium
Surfactant laxative - for constipation (increase the wetting action)
Bisacodyl
Stimulant laxative

Opioid induced constipation, slow intestinal transit constipation
Magnesium hydroxide
Osmotic Laxative; Constipation, bowel clean out procedure or poisoning
Methotrexate
Disease modifying antirheumatic drugs - non-biologic (DMARDs) --

Rheumatoid arthritis (most common), cancer, psoriasis, Chron's disease, SLE
Etanercept
Disease modifying antirheumatic drugs (DMARDs) -Biologic

Rheumatoid arthritis, psoriasis, and other autoimmune diseases
Cyclosporine
Calcineurin Inhibitors

Prevent rejection of kidney, liver, and heart transplants (administered with glucocorticoid)

Also treats autoimmune diseases (psoriasis, RA)
Prednisone
Glucocorticoids

Adjunctive treatment of autoimmune diseases (RA, and SLE) during acute exacerbations. Suppression of allograft rejection
Penicillin
Beta Lactam

Susceptible bacterial infections (treatment and prophylaxis)

Drug of choice: Syphilis (T. Pallidum)
Cephalosporins
Beta Lactam

Susceptible bacterial infections (treatment and prophylaxis)

Examples: STI's, Acute Otitis Media, surgical prophylaxis (biggest use)
Carbapenems
Beta-lactam

Extremely broad spectrum for bacterial infections caused by highly resistant organisms
Vancomycin
Vancocin

Susceptible gram + bacterial infections

DOC: Healthcare-associated MRSA

Serious staphylococcal infections
Tetracycline
Atypical organisms (rickettsia, spirochetes); Lyme disease, Acne, PUD, periodontal disease
Erythromycin
Macrolides

Broad spectrum antibiotic (chlamydial infections, pneumonia caused by M pneumonia)
Gentamicin
Aminoglycosides

Serious gram-negative infections; gram positive infections for synergy only
Trimethoprim/ sulfamethoxazole
Tx and prophylaxis of:
UTI's, Pneumocystis Pneumonia
(PCP)
Ciprofloxacin
Fluroquinolones

Cover a lot of Broad spectrum - infections of lower respiratory tract, inner ear, soft tissue, and bone; UTI
clindamycin
Anerobic gram negative infections, aerobic gram positive infections
metronidazole
Anaerobic bacteria and sensitive protozoans (Giardia, Trichmonas)

DOC: for C. Difficile
acyclovir
1st line agent for most infections caused by HSV and VZV; herpes encephalitis (HSV)
Ganiciclovir
Prevention /treatment of cytomegalovirus in immune- compromised pts (e.g., CMV colitis, esophagitis, pneumonitis, retinitis)
Oselatamivir
Treatment of influenza A and B within 2 days of s/s; prophylaxis
Conventional Amphotericin B
Variety of fungal infections - Broad spectrum, DOC for MOST systemic mycoses; some protozoa

Polyene Antifungal
liposomal amphotericin B
Because of the cost, reserved for patients who have failed standard amphotericin or who will not/do not tolerate it secondary to nephrotoxicity
Itraconazole
Azole antifungal

Broad spectrum anti-fungal
Isoniazid
Active and Latent TB - bactericidal
Rifampin
Active and Latent TB

Bactericidal
Pyrazinamide
Active TB - in combination with other anti-TB medications for initial therapy
Ethambutol
Active TB in combination with other agents
Abacavir
Zidovudine
Nucleoside/tide reverse transcriptase inhibitor
HIV (backbone of therapy)

HBV (some NRTIs)

Prevention of perinatal transmission (Zidovudine)
Efavirenz
Non-nucleoside reverse transcriptase inhibitor

HIV
Darunavir
Protease Inhibitor (HIV)
Ritonavir; cobicistat
Both agents that are always used to boost PI's such as darunavir
Raltegravir
HIV integrase inhibitor
Enfurvitide
HIV fusion inhibitor

HIV unresponsive to other ART

Sub Q twice daily
maraviroc
CCR5 antagonist

R5-tropic HIV-1
tenofavir/emtricitabine (Truvada)
PrEP is pre-exposure prophylaxis
- - 1 tablet PO daily
Influenza vaccine
Inactivated influenza vaccine (intradermal or intramuscular)

LAIV (live attenuated influenza vaccine) -> intranasal
Pneumococcal polysaccharide vaccine (PPSV23)
Pneumovax 23
Who should get the flu vaccine?
- Humans over 6 months of age - everybody!!!! At minimum: highest risk populations: children, Aspirin therapy, pregnancy women, elderly people, obese, long term care, immunosuppressed, asthma, anemia, diabetes
Who should be vaccinated for pneumococcal?
- Immunocompromised patients with chronic disease, smokers, long term care facilities
- And patients older than 65 who have not been previously vaccinated - wide range!!! Many seen in the in-patient setting
Other sets by this creator