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PHARM L17/18: Neurodegenerative Disorders, Psychotherapeutic Drugs

Terms in this set (16)

What is the choice drug for treating Parkinson's disease?
Levadopa
Describe the pathophysiology of Parkinson's disease.
progressive neurodegenerative movement disorder due to loss of dopaminergic neurons in the substantia nigra
Which drug is a GABA uptake blocker used to treat ALS?
A) Baclofen
B) Gabapentin
C) Baclofen
D) Riluzole
E) Prednisone
D) Riluzole
Which drug is used to control spasticity in patients with ALS?
A) Tinzanidine
B) Baclofen
C) Riluzole
D) Gabapentin
E) None of the above
B) Baclofen
Which drug can be used to treat spasticity in both ALS and MS?
A) Tinzanidine
B) Baclofen
C) Riluzole
D) Gabapentin
E) None of the above
B) Baclofen
Describe the early signs and symptoms of ALS
• muscle atrophy, weakness in legs
• muscle twitching
• slurred speech
• difficulty keeping good posture
*does not usually affect bowel/bladder control
What is the most common cause of death in patients with ALS?
respiratory failure
Name the three cholinesterase inhibitors used to treat symptoms of Alzheimer's disease
Donepezil
Galantamine
Rivastigme
*inhibit ACh breakdown
*as disease progresses, brain produces less ACh so drug becomes less effective
*these treat mild-moderate AD
Name the TYPICAL antipsychotic drugs used to treat symptoms of schizophrenia
Haloperidol
Chlorpromazine
Fluphenazine
Thioridazine
Thiothixene
Out of the typical antipsychotics used to treat schizophrenia, which one can cause cardiac- and retino-toxicity?
Thioridazine
What is the #1 side effect of long term use of antipsychotics in treatment of schizophrenia?
tardive dyskinesia
Which type of drug is used to treat depression and has lethal food-drug interactions?
Monoamine oxidase A inhibitors (MAOIs)
What are the three main NTs involved in depression?
serotonin, NE, DA
Name the main anti-mania drug prescribed for treatment of bipolar disorder
Lithium
Bipolar disorder is treated with 3 classes of medications. Name them.
Anti-mania
Antipsychotics
Antidepressants
What are the 2 main drugs used to treat ADHD?
Amphetamine
Methylphenidate
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