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34 terms

Exam 2 Antipsychotics/Anti-ADHD

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Risperdal
risperidone

Atypical Antipsychoitc
bipolar mania, schizophrenia, autism

tablet
oral solution
ODT - Remeron M-Tab
once or BID
Invega
paliperidone

Atypical antipsychotic

active metabolite of risperidone
Zyprexa
olanzapine

Atypical Antipsychotic
bipolar disorder, schizophrenia
tablet
ODT - Zyprexa Zydis
once daily
Seroquel
quetiapine

Atypical Antipsychotic
bipolar disorder, schizophrenia, depression add-on
tablet
BID
Seroquel XR
quetiapine

Atypical Antipsychotic
bipolar disorder, schizophrenia, depression add-on
ER tablet
once daily
Abilify
aripiprazole

Atypical Antipsychotic
bipolar disorder, schizophrenia, autism, depression add on

tablet
oral solution
ODT - Abilify Discmelt
once daily
Geodon
zaprasidone

Atypical Antipsychotic
bipolar disorder, schizophrenia
capsule
BID
Ambien
zolpidem

Imidazopyridine Hypnotic
insomnia
5, 10 mg tablet
once daily

zolpidem my cause sleep-driving, cooking or phone calls
Ambien CR
zolpidem

Imidazopyridine Hypnotic
insomnia
6.25, 12.5 mg ER tablet
once daily
*5 or 10 mg immediate release with remainder released 3 hours later to maintain sleep*
Edluar
zolpidem

Imidazopyridine Hypnotic
insomnia
5,10 mg sublingual tablet
once daily

zolpidem my cause sleep-driving, cooking or phone calls
Sonata
zaleplon

Pyrazolopyrimidine Hypnotic
insomnia
5, 10 mg capsule
once daily
Lunesta
eszopiclone

Cyclopyrrolone Hypnotic
insomnia
1, 2, 3 mg tablet
once daily

adverse effect = unpleasant aftertaste
Rozerem
ramelteon

Melatonin Receptor Agonist Hypnotic
insomnia
8 mg tablet
once daily
disorder characterized by difficulty in sustaining attention, poor concentration, poor time management, and often hyperactivity
Attention Deficit/Hyperactivity Disorder (ADHD)
Ritalin, Methylin
methylphenidate

CNS Stimulant - CII
Treatment of ADHD and narcolepsy in patients > 6yrs
5, 10, 20 mg tablet
BID or TID

Adverse Reactions = insomnia and nervousness
Ritalin LA
methylphenidate

CNS Stimulant - CII
Treatment of ADHD and narcolepsy in patients > 6yrs
10, 20, 30, 40 mg ER capsule (50% IR beads, 50% DR beads)
once daily
IR beads released immediately and DR beads released 4 hours later
Concerta
methylphenidate

CNS Stimulant - CII
Treatment of ADHD and narcolepsy in patients > 6yrs
18, 27, 36, 54 mg ER tablet
once daily

*outer drug overcoat surrounding an osmotic core
drug overcoat dissolves within one hour for initial dose, then released in controlled rate from osmotic core*

*empty tablet shell may appear in stool*
Metadate CD
methylphenidate

CNS Stimulant - CII
Treatment of ADHD and narcolepsy in patients > 6yrs

10, 20, 30, 40, 50, 60 mg ER capsule
once daily
IR and ER beads - 30% released immediately and 70% released more slowly
Daytrana
methylphenidate

CNS Stimulant - CII
Treatment of ADHD and narcolepsy in patients > 6yrs

10, 15, 20, 30 mg transdermal
apply to hip 2 hours before effect needed
remove after 9 hours
new system applied each morning
Focalin
dexmethylphenidate

CNS Stimulant - CII
ADHD
dextro isomer = active isomer of methylphenidate

2.5, 5, 10 mg tablets
BID
patients switching from methylphenidate to dexmethylphenidate should:
start with half their methylphenidate dose and titrate up
Focalin XR
dexmethylphenidate

CNS Stimulant - CII
ADHD
dextro isomer = active isomer of methylphenidate

5, 10, 15, 20, 30 mg ER capsules
once daily

30 minute onset of action for ADHD
detroamphetamime bound to lysine

pro-drug cleaved by GI enzymes
lisdexamfetamine
Vyvanse
lisdexamfetamine

CNS Stimulant - CII
ADHD

20, 30, 40, 50, 60, 70 mg capsules
once daily
Strattera
atomoxetine

Selective Norepinephrine Reuptake Inhibitor
not controlled
ADHD

10, 18, 25, 40, 60, 80, 100 mg capsules
once or BID
mechanism of action of atomoxetine
increases the availability of norepinephrine by blocking norepinephrine reuptake
hormone essential in regulating attention, impulse control and organization
norepinephrine
Intuniv
guanfacine

Not controlled
ADHD
1, 2, 3, 4 mg ER tablet
once daily

start with 1 mg dose and adjust in increments of 1mg/week
Adverse effects = bradycardia, hypotension, and syncope
Tenex
guanfacine

hypertension
tablet
Kapvay
clonidine

non-controlled
ADHD
0.1, 0.2 mg ER tablets
once daily

start with 0.1 mg dose and adjust in increments of 0.1 mg /week

Adverse effect = hypotension
Adderall
amphetamine, dextroamphetamine combo

CNS Stimulant - CII
ADHD and narcolepsy
5, 7.5, 10, 12.5, 15, 20, 30, mg tablet
once or BID
Adderall XR
amphetamine, dextroamphetamine combo

CNS Stimulant - CII
ADHD and narcolepsy
5, 10, 15, 20, 25, 30 mg ER capsule
once daily
Provigil
modafinil

CNS Stimulant - CIV
narcolepsy, shift work sleep disorder (SWSD)
100, 200 mg tablet
once daily
Nuvigil
armodafinil

CNS Stimulant - CIV
narcolepsy, shiftwork sleep disorder (SWSD)
R-isomer of modafinil
50, 150, 250 mg tablets
once daily