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Bleeding disorders in children
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Hematopoiesis begins at ______________________ of gestation with erythropoiesis in the ____________
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3 weeks
yolk sac.
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Hematopoiesis begins at ______________________ of gestation with erythropoiesis in the ____________
3 weeks
yolk sac.
By 2 months' gestation, the primary site of hematopoiesis migrates to the ________________
liver
By 5 to 6 months' gestation, the process shifts from the liver to the ________________
bone marrow.
As the child grows, hematopoiesis moves to the
central bones of the body (vertebrae, sternum, ribs, and pelvis), and the marrow is gradually replaced with fat.
During the third trimester,
gamma chain production gradually diminishes, replaced by beta chains, resulting in hemoglobin A (α2β2).
