Dimorphic Systemic Fungi
Histo, Blasto, and Cocci,
mold at room temp and yeast at 37
Histoplasma Capsulatum what type of cultures??
Bone marrow, respiratory specimen, blood cultures
Ohio and Mississippi
How long does Histo take to grow
Appearance in Tissues
2-4 microns, INTRACELLULAR in macrophages, smaller than Blasto
Type of Media
fungal media with cycloheximide, which enhances
Must be differentiated from?
Sepedonium which is not dimorphic
8-15 double walled, no macroconidia
BLASTO culture from
BLAST at 37? at RT?
37 it is rounded (cotton seed) and RT it looks like lollipops
cotton seed agar; converts Blasto
COCCIDIOIDES IMMITIS grows?
in 5 days
San Juoquin Valley Fever or Desert Valley Fever
Appearance in tissue
hyphae fragments- reproductive cells (sporolates); highly infectious
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