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El Maestro File (Antibiotics) - only highlighted questions

Terms in this set (13)

Which procedure least likely to produce bacteremia?

extraction,
non-surgical endo,
oral prophylaxis
oral prophylaxis
QUESTION: Pt had hip replacement 10 years ago, what do you use to premeditate?
No premedication needed
QUESTION: Pt needs antibiotic prophylaxis. He is taking penicillin already, what do you give him?

OLD GUIDELINES - eugene
Clindamycin
---
now give azithro or clarithro
QUESTION: Pt is taking an antibiotic, which is metabolized in the liver. Metabolism of this antibiotic is decreased by which drug?
a. TCA
b. SSRI
c. phenothiazine
d. diazepam
d. diazepam
QUESTION: Penicillin, why is this so good to give as an antibiotic?
(toxicity, price?)
Low toxicity, cheap
QUESTION: What antibiotic used for endo, pulpal involvement?
PEN VK (yes it actually says VK together)
QUESTION: Tetracycline mechanism of action:
protein synthesis inhibitor (30s),
bacteriostatic
QUESTION: Tetracycline does not do one of the following:

reduce host response
reduce bacterial infection
reduce host collagenase
decrease gingival crevicular fluid flow
decrease gingival crevicular fluid flow
Minocycline & Doxycycline: all is true except?

Both increase GCF secretion,
both released in GCF (Gingival crevicular fluid)
Both true

- tetracycline is more concentrated in GCF more than in blood
QUESTION: Child comes in with an oral infection and is NOT allergic to Pen. What do you prescribe?

a. Penicillin
b. Amoxicillin
c. Tetracycline
b. Amoxicillin
Pt is taking tetracycline. Which of the following drugs would be contraindicated?
Penicillin
---
Clinically important antagonism has been reported between penicillin and tetracycline against pneumococci,9,10 penicillin and erythromycin against group A streptococci11 and ampicillin, streptomycin and chloramphenicol in acute bacterial meningitis.
QUESTION: What happens when you have penicillin and decide to prescribe tetracycline with it?
Tetracycline will decrease the efficacy of Penicillin.

- Don't do it. Tetracline is bacteriostatic whereas penicillin is bacteriocidal. The two mechanisms of action (CIDAL+STATIC) cancel each other out because when you need bacterial growth to actually use penicillin, but you don't have that growth when you prescribe Tetracycline. ANTAGONISTS
QUESTION: Pseudomonas colitis:
c. difficile and clindamycin
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