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PATHO FINALS REVIEWER

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Cellular adaptation

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Terms in this set (102)

Cellular adaptation

Occurs when excessive physiologic stresses or
pathologic stimuli result in a new but altered steady
state

Reversible cell injury

Pathologic changes that can be reversed when the stimulus is removed, or if the cause of the injury is mild

IRREVERSIBLE CELL INJURY

Pathologic changes which are permanent and will cause cell death with certainty

Implies failure of adaptive mechanisms ² the intensity of WKHDGYHUVHVWLPXOXVPD\KDYHH[FHHGHGWKHFHOO·V adaptive capacity

1. ATP Depletion
2. Oxidative Stress
3. Increase in Cytosolic Calcium
4. Cell Membrane Permeability Defects
5. Mitochondrial Injury

What are the 5 Mechanisms of Injury