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Drugs for PUD

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Peptic Ulcer Disease

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Terms in this set (31)

Peptic Ulcer Disease

- erosions/ulcerations in the stomach and duodenum
- imbalance between mucosal defensive and aggressive factors

agressive factors

- Helicobacter pylori
- NSAIDsL break down lining by inhibiting prostaglandins
- acid
- pepsin
- smoking

defensive factors

- mucus
- bicarb
- blood flow
- prostaglandins

goals of therapy

- alleviate symptoms
- promote healing
- prevent complications
- prevent reoccurrence
- drug therapy creates conditions that promote healing --> does NOT later the disease process

actions of antiulcer drugs

- eradicate H. pylori
- reduce gastric acid
- enhance mucosal defenses