Try Magic Notes and save time.
Try it free
Try Magic Notes and save time
Crush your year with the magic of personalized studying.
Try it free
hello quizlet
Home
Subjects
Expert Solutions
Log in
Sign up
Science
Medicine
Rheumatology
MedPath II - Rheumatology I
5.0 (1 review)
Flashcards
Learn
Test
Match
Q-Chat
Get a hint
What is the difference between Acute & Chronic autoimmune dz?
Click the card to flip 👆
Acute dz: Ex. Gout
Initiator: Exogenous stimuli
Self-limited by removing offending agent
Flares: re-exposure to initiator
Chronic Dz: SLE
Initiator: no longer recognizable
Autoimmunity ---> tissue damage
Flares are frequent: no longer require an initiator
Click the card to flip 👆
1 / 128
1 / 128
Flashcards
Learn
Test
Match
Q-Chat
Created by
gsamiratedu7
Share
Share
Terms in this set (128)
What is the difference between Acute & Chronic autoimmune dz?
Acute dz: Ex. Gout
Initiator: Exogenous stimuli
Self-limited by removing offending agent
Flares: re-exposure to initiator
Chronic Dz: SLE
Initiator: no longer recognizable
Autoimmunity ---> tissue damage
Flares are frequent: no longer require an initiator
Autoimmune disease is tissue injury caused by?
immunologic rxn of the organism against it own tissue.
This occurs due to failure of the body to:
•Sequestering of antigens
•Failure of normal regulatory processes (adaptive immunity)
Adaptive Immunity Pathway
Treg downregulate fails in autoimmune dz
Complement C3, C5, C7, C8, C9 - Often fails in autoimmune dz. backup to the cleanup (lysis & destruction)
In what dz does the autoantibody work on the immune complex, targeting the dsDNA?
SLE
In what dz does the autoantibody work on inactivation of the phospholipid beta-2 glycoprotein?
APS - Antiphospholipid syndrome
See more
