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Med. Surg. Nursing-Immune, Immunoglobulins

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IgG
Appears in serum and tissues
Assumes major role in bloodborne and tissue infections
Activates complement
Enhances phagocytosis
Crosses placenta
IgA
Appears in body fluids
Protect against respiratory, GI, and genitourinary infections
Prevents absorption of antigens from food
Passes through breast milk
IgM
Appears mostly in intravascular serum
Appears as first immunglobulin produced in response to bacterial and viral infections
Activates complement
IgD
Appears in small ammounts in serum
Possibly influences B-lymphocyte differentiation
IgE
Appears in serum
Takes part in allergic and some hypersensitivity reactions
Combats parasitic infections