Exam 1

Polystyrene Sulfonate
Side Effects:
Nursing Implications:
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Terms in this set (15)
Classification: Cationic exchange resins (Hypokalemic, electrolyte modifiers)

Indications: mild to moderate hyperkalemia

Action: Exchanges sodium ions for potassium Ions in the intestine. Reduce serum potassium levels

Contraindications: Life-Threatening Hyperkalemia, abnormal bowel function

Side Effects: F&E - Hypocalcemia, hypokalemia, sodium retention, hypomagnesemia. GI - intestinal necrosis, constipation, fecal impaction

Nursing Implications: Monitor for symptoms of hyperkalemia (fatigue, muscle weakness), Monitor for intestinal necrosis, Monitor serum potassium, Administer PO by 3 hrs before or 3 hrs after other medications
Classification: Heavy metal antagonists (antidotes)

Indications: Iron toxicity

Action: Removal of excess iron through the kidneys

Contraindications: Severe Renal disease,

Side Effects: Red urine, ototoxicity, hypotension, tachycardia, anaphylactic shock

Nursing Implications: monitor signs of iron toxicity, may cause oculotoxicity or ototoxicity, monitor serum iron, ferritin levels, liver function, crash cart
Classification: Chelating agents (antidotes)

Indications: Lead poisoning in children with blood lead levels >45 mcg/dL

Action: Decreased blood lead levels and decreased target organ damage in lead poisoning. Water soluble compound with lead to excrete through urine.

Contraindications: Lactation, renal failure, Lower doses in adults
Side Effects: nausea, vomiting, hypersensitivity reactions - Angioedema and urticaria

Nursing Implications:Assess family members for evidence of lead poisoning, Monitor neuro status, if patient Is unable to swallow the capsule, open capsule and sprinkle medicated beads on a small amount of soft food, or on a spoon followed my fruit juice
Classification: loop diuretic
Indications: Edema due to heart failure, hepatic impairment, or renal disease, hypertension

Action: Inhibits the reabsorption of sodium and chloride, increases renal excretion of water, sodium, chloride, magnesium, potassium and calcium

Contraindications: avoid in patients with alcohol intolerance

Side Effects: erythema multiforme, stevens-johnson syndrome, toxic epidermal necrolysis, aplastic anemia, agranulocytosis, dehydration, hypocalcemiam hypokalemia,hypomagnesemia, hyponatremiam hypovolemia, metabolic alkalosis

Nursing Implications: Assess fluid status. Daily Weight. Assess for tinnitus and hearing loss. Take with food or milk. daily weight
Classification: antianemics, vitamins

Indications: Vitamin B12 deficiency , pernicious anemia

Action: Corrects manifestations for pernicious anemia and vitamin B12 deficiency

Contraindications: hypersensitivity
Side Effects: anaphylaxis, heart failure, headache, hypokalemia

Nursing Implications: Monitor folic acid, vitaminB12, iron, Hgb and Hct, administer with other vitamins, administer with meals,
Classification: Anti-anemic

Indications: Iron deficiency in patients who cannot tolerate or receive oral iron

Action: Resolution of iron deficiency anemia

Contraindications: Anemia not due to iron deficiency

Side Effects: Seizures, hypersensitivity reactions

Nursing Implications: assess for signs and symptoms of anaphylaxis, toxicity and overdose
Classification: Biphosphonates

Indications: Treatment for osteoporosis

Action: Inhibits resorption of bone by inhibiting osteoclast activity

Contraindications: abnormalities of the esophagus which delay esophageal emptying, inability to stand/sit upright for at least 30 min

Side Effects: musculoskeletal pain, esophageal burn

Nursing Implications: administer in the morning 30 min before other medications, drinks and food
Classification: Fat-soluble

Indications: Treatment or prevention of vitamin D deficiency

Action: Requires activation in the liver and kidneys to create the active form of vitamin D3. Promotes absorption of calcium. Treatment of bone manifestations.

Contraindications: Hypercalcemia, Vitamin D toxicity
Side Effects: manifestations of hypercalcemia, pancreatitis, kidney stones

Nursing Implications: May be administered without regards to meals.
Classification: Appetite suppressants, anorexiant
Indications: Used to produce and maintain weight loss

Action: Inhibits the reuptake of both serotonin and norepinephrine.

Contraindications: mod to severe HTN, cardio disease, hyperthyroidism, glaucoma, history of drug abuse

Side Effects: HTN, Impotence, insomnia, and unpleasant taste may also occur.

Nursing Implications: People with diabetes may require an increased dose of insulin
Administer 30 min before meals or as a single dose before breakfast
Contact HCP if you feel chest pain, decreased exercise tolerance, fainting, or swelling of the legs
Monitor BP
Classification: Lipase Inhibitor

Indications: Obesity weight loss and maintenance when used with calorie deficit

Action: Decreases absorption of dietary fat by reversibly inhibiting lipase

Contraindications: malabsorption syndrome or cholestasis

Side Effects: abdominal pain, oily spotting, fecal urgency and incontinence, flatulence with discharge, fatty stools, and increased defecation.

Nursing Implications: take 4hrs apart from levothyroxine (decrease serum concentration)
Foods high in potassium
Supplemental vitamin ADEK 2hrs before or after dose
Sitagliptin *Classification*: *Indications*: *Action*: *Contraindications*: *Side Effects*: *Nursing Implications*:*Classification*: Antidiabetic *Indications*: Type 2 diabetes *Action*: Sitagliptin minimizes the rate of inactivation of the incretin hormones to increase hormone levels and prolong their activity. *Contraindications*: type 1 diabetes mellitus, insulin use, ketones in the urine, ESRD *Side Effects*: upper respiratory tract infection, stuffy or runny nose, sore throat, and headache. *Nursing Implications*: once daily with or without food assess glucoseRegular Insulin *Classification*: *Indications*: *Action*: *Contraindications*: *Side Effects*: *Nursing Implications*:*Classification*: antidiabetic, pancreatics *Indications*: Control hyperglycemia *Action*: Lowers blood glucose by increasing uptake of glucose in body cells *Contraindications*: Hypoglycemia *Side Effects*: hypoglycemia *Nursing Implications*: Assess for symptoms of hypoglycemiaGlyburide *Classification*: *Indications*: *Action*: *Contraindications*: *Side Effects*: *Nursing Implications*:*Classification*: antidiabetic, sulfonylureas *Indications*: Control blood sugar in type 2 diabetes *Action*: lowers blood glucose mainly by increasing secretion of insulin. *Contraindications*: hyper sensitivity to sulfa-based medications as well as sensitivity to glyburide itself. pregnancy, with renal or hepatic impairment, and critical illness *Side Effects*: hypoglycemia *Nursing Implications*: take before breakfast or divide doses before meals if experience gastric distressPropylthiouracil *Classification*: *Indications*: *Action*: *Contraindications*: *Side Effects*: *Nursing Implications*:*Classification*: antithyroid, thiomaides *Indications*: Treat hyperthyroidism, before thyroidectomy, before/after radioactive Iodine therapy, thyroid storm *Action*: Decreasing production or release of thyroid hormones *Contraindications*: Radioactive iodine in pregnancy and lactation, *Side Effects*: hypothyroidism, jaundice (jaundice), liver failure *Nursing Implications*: increase effect of anticoags (bleeding), take around the clock evenly, assess pulse rate, s/sx of liver failureLevothyroxine *Classification*: *Indications*: *Action*: *Contraindications*: *Side Effects*: *Nursing Implications*:*Classification*: hormones, thyroid preparations *Indications*: Hypothyroidism *Action*: Provide exogenous source of thyroid hormones *Contraindications*: hypersensitivity to active or extraneous constituents of the drug, thyrotoxicosis, and acute myocardial infarction *Side Effects*: S/Sx of hyperthyroidism *Nursing Implications*: in the morning on an empty stomach check pulse before administering