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Terms in this set (46)
How is herpes spread usually?
direct contact with infected secretions
Oral or genital? HSV-1
Oral or genital? HSV-2
Can HSV-2 be spread even if lesions aren't present, as long as that person is seropositive?
What is the most common presentation of HSV-1?
T/F HSV-2 can be spread through vaginal fluid?
Are men or women more likely to get herpes lesions?
Where can you get oral-labial herpes?
inside the oral mucosa and pharynx, also on the lips (usually milder and shorter)
What are a few symptoms that can accompany oral-labial herpes, according to the lecture?
tingling, burning, itching on lips
Is ocular herpes more likely to be HSV-1 or 2?
How does ocular herpes usually present?
UNILATERAL conjunctivitis, blepharitis, or corneal epithelial opacities
What can reoccurrence or ocular herpes lead to?
scarring and blindness
A 24 year old female presents to the clinic complaining of a fever and "feeling tierd". She says she has been sexually active and has had 8 partners over the last year. She has not had a pelvic exam in 2 years. If you suspect herpes, what other symtoms would you expect to find?
vesicular lesions on vulva, perineum, butt, cervix, or vagina
What population do you most commonly see perianal and anal herpes in?
What are some symptoms of anal/perianal herpes? (8)
When do babies have the highest risk of neonatal infection?
when the mother has a primary infection (as opposed to reoccurrence)
What does neonatal herpes present as?
vesicles or conjuncivities
syndrome similar to sepsis
What is the method of choice to diagnose herpes?
What is another way to diagnose Herpes, that is not usually used, but a good question for boards?
What is the standard treatment for herpes?
acyclovir 400 mg 5x/day
You have a patient who says she is terrible at remembering to take meds. What med might you give her for herpes?
Why might you give someone treatment for herpes if it is not going to cure the disease?
to shorten the symptoms when they have reoccurrence.
Prophylaxis (may prevent shedding of the virus)
What causes shingles (herpes zoster)?
reactivation of VZV
Who is at an increased risk for shingles?
immunosuppressed, older age, those who have had chicken pox
Where does the rash in chicken pox start usually?
face or trunk
How do you transmit chicken pox?
by simply being in the same room as someone who is infected (think "chicken pox parties"
How do you transmit shingles?
You must touch the infected persons rash
Where does the VZV sit before it turns into shingles?
What is shingles preceded by usually?
PAIN in a dermatome usually
is shingles usually unilateral or bilateral?
unilateral, often on thorax
what is the most common complication of shingles?
How can you prevent Shingles?
-vaccinate for VZV
-Zostavax for the older population
How do you prevent herpes zoster in immunosuppressed?
How can you treat herpes zoster?
give acyclovir/valacyclovir/famciclovir early on
predisone may help possibly
How do you transmit CMV?
close contact with infected person (secretions or blood)
What population is CMV mono most common in?
sexually active young adults
What 2 symptoms are present in most with CMV mono?
headache and splenomegaly
T/F CMV infection is common in transplant patients
How do you diagnose CMV and VZV?
Clinical grounds most often
How do you treat CMV?
ganciclovir and valganciclovir
What is the most common presentation of EBV?
What do patients who EBV mono present with?
fever, pharyngitis and lymphadenopaty
What do you see in immunocomprimised patients with EBV?
hairy leukoplakia (raised white lesions on lateral aspect of tongue)
What labs do you commonly seen in EBV mono?
thrombocytopenia and abnormal LFTs
peripheral blood lymphocytosis with >10% atypical lymphocytes
How do you diagnose EBV?
Detect heterophile Ab
abnormal lymphocytes on smear
How do you treat EBV?
corticosteroids my help if impending airway obstruction, severe thrombocytopenia, or hemolytic anemia
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