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What is 1 + 3?
alpha1>>>alpha2. Good antihypertensive.
alpha1>alpha2, irreversible and long duration.
alpha1=alpha2, older drug and not used much anymore.
alpha2>>alpha1. Reverses a2as.
beta1=beta2>=alpha1>alpha2. Used in heart failure.
Metoprololol, Acebutolol, Atenolol
beta1>>>beta2, mainly affects heart.
beta1=beta2, don't want to antagonize beta2 (b/c stop bronchodilation) so not as useful.