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5 Written questions

5 Matching questions

  1. Disorders of immunoglobulins
  2. Complement disorders
  3. Dosing for epinephrine for shock but w/ pressure
  4. Drug allergy: dextran & hydroxyethyl starch
  5. Amyloidosis
  1. a Hereditary angioedema
  2. b Deficiencies:
    X-linked agammaglobulinemia
    Acquired hypoimmunoglobulinemia
    Selective immunoglobulin A deficiency
    Cold autoimmune diseases
    Multiple myeloma
    Waldenstrom's macroglobulinemia
  3. c Accumulation of insoluble fibrillar proteins amyloid in heart, vascular smooth muscle, kidneys, adrenals, GI, nerves, and skin
  4. d Allergy‐ dextran may react w/ antibodies to viral or bacterial polysaccharides
    Anaphylactoid‐ dextran may activate compliment
  5. e 0.01 mg - 0.1 mg IV. Do not give 1 mg!

5 Multiple choice questions

  1. Proliferation of single clone B‐ lymphocytes->immune complex deposition
  2. Antihistamines & epinephrine doesn't work
    C1 esterase inhibitor
  3. Degranulations & release of vasoactive mediators->hypotension & CV collapse
  4. ↑d incidence in medical personnel (15% in
    Patients w/ multiple surgeries, fruit (banana)
    allergies & spina bifida
    Potential for delayed reaction (>30 minutes)
  5. O2, IV fluids, epinephrine, H1 antagonists, steroids

5 True/False questions

  1. Effects of anaphylaxisMast cell/basophil degranulation->release of
    histamine, prostaglandins, & leukotrienes->vasodilation & ↑d capillary permeability->hypotension, bronchoconstriction & CV


  2. Waldenstrom's macroglobulinemiaCold agglutinins->activation of compliment & plts, hyper‐viscosity, renal failure


  3. Type 1 allergic reaction-hypersensitivity reactionItching, conjunctivits, rhinitis, laryneal & angioedema, urticaria, bronchospasm (asthma), dysrhythmias, hypotension, GI cramps & malabsorption


  4. Cold hemagglutinin disease‐Abnormal proteins agglutinate in response to cold
    Cold hemagglutinin disease


  5. Drug toxicityAntigen-antibody, hypotension, bronchospasm, urticaria, unpredictable severity, prior exposure, rapid onset, not dose related, low incidence