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5 Written questions

5 Matching questions

  1. Dosing for epinephrine
  2. Leukotriene effects
  3. Complement disorders
  4. Dosing for full shock with cardiopulmonary arrest may need
  5. IgM‐
  1. a 1 mg 1:1000
    0.01 mg/kg IM
    Max 0.5 mg in adult
    Max 0.3 mg in child
  2. b Capillary permeability
    Negative inotropy
    Coronary artery vasoconstriction
  3. c Lysis of bacterial cell walls
  4. d 1 mg IV
  5. e Hereditary angioedema

5 Multiple choice questions

  1. Massive degranulation of mast cells & basophils
  2. Rare, accounts for 1% of adverse reactions to locals
    Ester based->PABA
    Preservatives (methylparaben, propylparaben) similar to PABA
    No proven cross-reactivity between ester & amides
  3. Antihistamines & epinephrine doesn't work
    C1 esterase inhibitor
  4. Proliferation of single clone B‐ lymphocytes->immune complex deposition
  5. Itching, conjunctivits, rhinitis, laryneal & angioedema, urticaria, bronchospasm (asthma), dysrhythmias, hypotension, GI cramps & malabsorption

5 True/False questions

  1. Treatment of anaphylactoid reactionsSimilar to anaphylaxis


  2. Cold autoimmune diseasesAbnormal proteins agglutinate in response to cold
    Cold hemagglutinin disease


  3. Drug allergyHalothane hepatitis- trifluoroacetyl halide metabolites + hepatic microsomal proteins->neoantigens
    Sevo doesn't produce oxidative halide metabolites


  4. What triggers angioedemaEmotional stress triggers 30-40% of attacks


  5. Anaphylactoid reactionsNot IgE mediated, similar clinical presentation, don't need prior sensitization