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5 Written questions

5 Matching questions

  1. Leukotriene effects
  2. Dosing for full shock with cardiopulmonary arrest may need
  3. Type 2 hypersensitivity reaction cytotoxic hypersensitivity
  4. Drug allergy: latex
  5. Anaphylaxis primary exposure
  1. a Capillary permeability
    Negative inotropy
    Coronary artery vasoconstriction
  2. b ↑d incidence in medical personnel (15% in
    Patients w/ multiple surgeries, fruit (banana)
    allergies & spina bifida
    Potential for delayed reaction (>30 minutes)
  3. c Antigens are normally endogenous, although exogenous chemicals (haptens) which can attach to cell membranes
    Drug-induced hemolytic anemia, granulocytopenia & thrombocytopenia
    IgM & IgG mediated
    Phagocytes & K cells play a role
  4. d Sensitization via antigen specific IgE antibodies
  5. e 1 mg IV

5 Multiple choice questions

  1. Mast cell/basophil degranulation->release of
    histamine, prostaglandins, & leukotrienes->vasodilation & ↑d capillary permeability->hypotension, bronchoconstriction & CV
  2. Anaphylaxis‐ IgE mediated reaction
    Rhinitis‐ IgE mediated
    Food & drug allergies
  3. Barbs‐ rare, severe
    Propofol- egg lecithin emulsion, most common, high incidence of bronchospasm
  4. Secretions, topical defense
  5. 1-600 adults, sinus & pulm infections, risk during blood transfusion (anti-IgA antibodies)

5 True/False questions

  1. Precautions and prophylaxis for latex allergiesLatex free OR environment
    H1, H2 blockers, corticosteroids may be considered


  2. Hereditary angioedemaAirway emergency
    C1 esterase inhibitor->poorly regulated compliment activation->release of vasoactive mediators (bradykinin)->episodic airway edema


  3. IgE‐Secretions, topical defense


  4. Cryoglobulinemia‐Cold agglutinins->activation of compliment & plts, hyper‐viscosity, renal failure


  5. Anaphylactoid reactionsDegranulations & release of vasoactive mediators->hypotension & CV collapse