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5 Written questions

5 Matching questions

  1. S/S of anaphylactoid reactions
  2. Cryoglobulinemia‐
  3. Amyloidosis
  4. Treatment for hereditary angioedema
  5. Drug allergy: Induction drugs
  1. a Cold agglutinins->activation of compliment & plts, hyper‐viscosity, renal failure
  2. b Barbs‐ rare, severe
    Propofol- egg lecithin emulsion, most common, high incidence of bronchospasm
  3. c Antihistamines & epinephrine doesn't work
    FFP
    C1 esterase inhibitor
    Antifibrinolytics
  4. d Accumulation of insoluble fibrillar proteins amyloid in heart, vascular smooth muscle, kidneys, adrenals, GI, nerves, and skin
  5. e Degranulations & release of vasoactive mediators->hypotension & CV collapse

5 Multiple choice questions

  1. 1 mg IV
  2. Manifestations dependent upon drug
    Fairly predictable
    No prior exposure needed
    Dose related
    Onset may be delayed
    Common
  3. Airway emergency
    C1 esterase inhibitor->poorly regulated compliment activation->release of vasoactive mediators (bradykinin)->episodic airway edema
  4. Similar to anaphylaxis
  5. Airway‐ macroglossia
    CV‐ conduction disturbance, RHF
    Renal‐ nephrotic syndrome
    Nerves‐ autonomic neuropathy, nerve compression

5 True/False questions

  1. Platelet activating factor effectsBronchoconstriction

          

  2. Dosing for epinephrineManifestations dependent upon drug
    Fairly predictable
    No prior exposure needed
    Dose related
    Onset may be delayed
    Common

          

  3. What triggers angioedemaAirway emergency
    C1 esterase inhibitor->poorly regulated compliment activation->release of vasoactive mediators (bradykinin)->episodic airway edema

          

  4. Drug allergy: latex↑d incidence in medical personnel (15% in
    anesthesiologists)
    Patients w/ multiple surgeries, fruit (banana)
    allergies & spina bifida
    Potential for delayed reaction (>30 minutes)

          

  5. Prostaglandins effectsCapillary permeability
    Vasodilation
    Bronchoconstriction

          

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