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5 Written questions

5 Matching questions

  1. What triggers angioedema
  2. IgM‐
  3. Type 2 hypersensitivity reaction cytotoxic hypersensitivity
  4. Drug allergy: protamine
  5. Drug allergy: latex
  1. a Lysis of bacterial cell walls
  2. b ↑d incidence in medical personnel (15% in
    anesthesiologists)
    Patients w/ multiple surgeries, fruit (banana)
    allergies & spina bifida
    Potential for delayed reaction (>30 minutes)
  3. c Derived from salmon semen
    ↑d incidence in pts allergic to seafood, diabetics, vasectomized males)
    Protamine induced compliment activation->thromboxane->bronchoconstriction & pulm HTN (↑d PAP)
    Peripheral vasodilation
  4. d Antigens are normally endogenous, although exogenous chemicals (haptens) which can attach to cell membranes
    Drug-induced hemolytic anemia, granulocytopenia & thrombocytopenia
    IgM & IgG mediated
    Phagocytes & K cells play a role
  5. e Emotional stress triggers 30-40% of attacks

5 Multiple choice questions

  1. Massive degranulation of mast cells & basophils
  2. Mast cell/basophil degranulation->release of
    histamine, prostaglandins, & leukotrienes->vasodilation & ↑d capillary permeability->hypotension, bronchoconstriction & CV
    collapse
  3. Airway‐ macroglossia
    CV‐ conduction disturbance, RHF
    Renal‐ nephrotic syndrome
    Nerves‐ autonomic neuropathy, nerve compression
  4. Deficiencies:
    X-linked agammaglobulinemia
    Acquired hypoimmunoglobulinemia
    Selective immunoglobulin A deficiency
    Cold autoimmune diseases
    Multiple myeloma
    Waldenstrom's macroglobulinemia
  5. Antihistamines & epinephrine doesn't work
    FFP
    C1 esterase inhibitor
    Antifibrinolytics

5 True/False questions

  1. Cold autoimmune diseasesHereditary angioedema

          

  2. Anaphylactoid reactionsNot IgE mediated, similar clinical presentation, don't need prior sensitization

          

  3. Type 1 allergic reaction-hypersensitivity reactionItching, conjunctivits, rhinitis, laryneal & angioedema, urticaria, bronchospasm (asthma), dysrhythmias, hypotension, GI cramps & malabsorption

          

  4. IgE‐Mast cells, Anaphylaxis and allergy

          

  5. Treatment for anaphylaxisMast cell/basophil degranulation->release of
    histamine, prostaglandins, & leukotrienes->vasodilation & ↑d capillary permeability->hypotension, bronchoconstriction & CV
    collapse