7220 Exam I Formulas to Memorize

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dose of new dosage form =

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(amount of drug absorbed from current dosage form)/(F of new dosage form)

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Terms in this set (10)

dose of new dosage form =

(amount of drug absorbed from current dosage form)/(F of new dosage form)

administration rate (Ra) =

SFD/𝛕

fu =

(free drug concentration)/(total drug concentration)

C free / (C bound + C free)

Cl =

VK

OR

SFD/Css ave

Incremental Loading Dose =

[V(C desired - C initial)]/SF

fraction of steady state achieved at time t =

1 - e^(-kt)

New CrCl =

(old CrCl) x (old SCr/new SCr)

weights used for CrCl

- underweight: ABW
- normal weight: ABW
- obese (30-39.99): AdjBW
- morbidly obese (≥40): LBW

Schwartz Equation

GFR (mL/min/1.73 m²) = [(k)(height in cm)]/SCr

pre-term infants up to 1 year: 0.33
full-term infants up to 1 year: 0.45
1-12 years: 0.55
13-21 year female: 0.55
13-21 year male: 0.70

Schwartz Bedside Equation

GFR (mL/min/1.73 m²) = [0.41(height in cm)]/SCr

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