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Pharmacology Key Terms

Terms in this set (14)

Anti - Inflammatory
? Function ?
- Mechanism?
Reduce Inflammation
- Mechanism
- Inhibit COX enzymes
- Cox enzymes
- Responsible for synthesizing inflammation molecules (LIKE PROSTAGLANDINS)
- So
- No COX = No Inflammation
Acetaminophen
Trade Names
- Tylenol
- Paracetamol
Fluid Retention think...
Heart Problems First! (Heart Work Overload)
Peripheral Edema (Leg Swelling)
Teratogenicity
BIRTH DEFECTS during pregnancy
Kidney vs Liver Names
Kidney = NEPH, RENAL
Liver = HEP
Bronchospasm
- What is this?
Coughing
Analgesic
? Function ?
- Function
- Treat Pain
Anti - Pyretic
? Function ?
Reduce Fever
Ibuprofen
? Trade Name(s) ?
- Trade Name(s)
- Advil
- Motrin
Naproxen
? Trade Name(s) ?
- Trade Name(s)
- Aleve
Ketorolac
? Trade Name(s) ?
- What's special about ketorolac?
- Trade Name(s)
- Toradol
- Special
- Administered thru IV; means its safer than opioids to treat post - op surgery pain
Indomethacin
? Trade Name(s) ?
- What's special about Indomethacin?
- Trade Name(s)
- Indocin
- Special
- Used to CLOSE infant PFO (patent foreamen ovale)
- PFO = Hole between L & R Atrium (Upper chambers of the heart) that is supposed to close right after birth
Celecoxib
? Trade Name(s) ?
- What's special about Celecoxib?
- Trade Name(s)
- Celebrex
- Special
- Treat symptoms of arthritis
- Joint Pain, Swelling, Inflammation
GI Upset & Ulcers & Bleeding
- Mechanism?
- Contraindications?
- Prevent?
- Bleeding Mechanism
- Inhibit platelet cyclooxygenase
- Leads to no forming of thromboxane AZ
- Leads to no platelet blood formation / aggregation aka bleeding
- Mechanism
- Reduces protective mucosal lining of gut; leads to gut being more susceptible to stomach acid which leads to
- Leads to N/V/D/BS/ AD(Nausea, Vomiting, Diarrhea, Bloody Stools/ Abdominal Discomfort)
- Prevent with:
- Taking with food, water, and NO ALCOHOL

- Bleeding!
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