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chapter 25 (exam 2)

Terms in this set (24)

this encodes for reverse transcriptase, endonuclease, and protease activities
pol
this encodes a poly-protein found at high levels in infected cells and is subsequently cleaved to form p17 and p24, both of which are associated with viral particles
gag
this encodes for a polyprotein with numerous glycosylation sites
env
the core of the virus includes a major structural protein called
p24
the major core structural protein on the gag gene
p24
the enzyme that enables the virus to convert viral RNA into DNA;
reverse transcriptase
this stands for small open-reading frame and it induces antibody production in the natural course of infection
sor gene
this initiate the infectious process when the gp120 protein on the viral envelope binds to the protein receptor called CD4
target cells
this virus has been isolated from blood, semen, vaginal secretions, saliva, tears, breast milk, cerebrospinal fluid, amniotic fluid, and urine but only blood, semen, vaginal secretions, and breast milk have been implicated in the transmission of _____ to date;
HIV
the range for clinical latency is __ to ___ years with a median of ____ years
7 to 11 years

10 years
that the absolute number of ________ lymphocytes continues to diminish as the AIDS disease progresses
CD4 + T
the most frequent malignancy observed in AIDS patients
Kaposi's sarcoma
Under Cryptosporidiosis know that the disease is caused by the parasite....
Cryptosporidium parvum
the progressive decline of CD4+ cells leads to a general decline in ______ function and is the primary factor in determining the clinical progression of _____
immune

AIDS
this virus is established by detecting antibodies to the virus, viral antigens, or viral RNA-DNA or by the gold standard which is viral culture
HIV
the __________ test is for antibody detection;
standard
testing assays are categorized into three main types which are
detection of HIV antibodies, antigens(p24), and detection or quantification of viral nucleic acids
know that for HIV-1 antibodies the confirmatory test is the?
western blot
IMMUNODEFICIENCY know that antibodies to HIV can be detected by ____
EIA
antibody testing by EIA remains the standard method for screening potential _______ _______
blood donors
the WB assay is based on the recognition of the major HIV proteins......
p24, gp41, and gp120/160
know that a positive result is indicated by the presence of any two of the bands
p24, gp41, and gp 120/160
the CDC estimates ____ million people in the U.S. are living with _____ infection
1.2 million

HIV
the CDC has issued a new testing recommendation making ____ __________ a routine part of medical care for all patients ____ to ___ years of age .
HIV screening

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