5 Written questions
5 Matching questions
- Electrical synapses
- small clear-core vesicle
- mini end plate potentials (MEPPS)
- syntaxin and SNAP-25
- Gap Junctions
- a make up EPPS and correspond to the release of just one or two vesicle. Small, happen spontaneously, and cannot trigger an AP.
- b Vesicles that contain small molecule neurotransmitters. These vesicles appear clear in electron micrographs. Made in the axon terminal by enzymes shipped down by slow axonal transport from the soma.
- c T-SNARE proteins embedded to the pre-synapatic membrane; attach to synaptic vesicles for vesicle fusion
- d Make electrical synapses possible. Consists of hexameric subunits made up of subunits called connexons.
- e Work by allowing ionic current to flow PASSIVELY through the gap junction pores from one neuron to the next. Very fast transmission.
5 Multiple choice questions
- recycling process for synaptic vesicle. Process takes about 1 minute.
- neuromuscular junctions when synapses from the pre-synaptic axon elaborate and appear in a saucer-like shape on the muscle fiber
- a very important protein involved in endocyctotic budding of vesicles from the plasma membrane. Assemble together (by polymerization) to form membrane coats during the budding of the phase synaptic vesicle cycle.
- a kinase that phosphorylates synapsin and causes it to let go of the synaptic vesicles it is holding in the reserve pool
- A neurotransmitter found primarily at neuromuscular junctions of the striated muscles and in the visceral motor system. Involved in muscle contraction and heart rate increases.
5 True/False questions
synapsin → reversibly binds to synaptic vesicles and may cross link vesicle to actin filaments in the cytoskeleton to keep the vesicles tethered within the reserve pool.
Neurotransmitters → chemical agents acting as messengers between the communicating neurons. Released from vesicle when the is a large Ca++ influx into the cell. How many are released depends on how much Ca++ enters the terminal.
hsc-70 → partially blocks post synaptic ACh receptors when placed in the extracellular medium. Used to study EPPs and MEPPs.
co-transmitters → chemical agents acting as messengers between the communicating neurons. Released from vesicle when the is a large Ca++ influx into the cell. How many are released depends on how much Ca++ enters the terminal.
SNAPs (soluble NSF-attachments proteins) → an ATPase involved in priming synaptic vesicle for fusion