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5 Written questions

5 Matching questions

  1. end plates
  2. synaptobrevin
  3. mini end plate potentials (MEPPS)
  4. acetylcholine (ACh)
  5. Electrical synapses
  1. a make up EPPS and correspond to the release of just one or two vesicle. Small, happen spontaneously, and cannot trigger an AP.
  2. b Work by allowing ionic current to flow PASSIVELY through the gap junction pores from one neuron to the next. Very fast transmission.
  3. c A neurotransmitter found primarily at neuromuscular junctions of the striated muscles and in the visceral motor system. Involved in muscle contraction and heart rate increases.
  4. d a V-SNARE protein that binds to the synaptic vesicle before exocytosis
  5. e neuromuscular junctions when synapses from the pre-synaptic axon elaborate and appear in a saucer-like shape on the muscle fiber

5 Multiple choice questions

  1. partially blocks post synaptic ACh receptors when placed in the extracellular medium. Used to study EPPs and MEPPs.
  2. membrane potential on an end plate large enough to trigger an action potential
  3. a protein that causes the final pinching-off of the membrane that completes the production of coated vesicles in the synaptic vesicle cycle.
  4. a SNARE protein on the surface of the synaptic vesicle. Binds Ca++ at concentrations similar to those required to trigger vesicle fusion, basically allowing it to act as a Ca++ sensor and triggering fusion.
  5. T-SNARE proteins embedded to the pre-synapatic membrane; attach to synaptic vesicles for vesicle fusion

5 True/False questions

  1. large dense-core vesiclesVesicles that contain small molecule neurotransmitters. These vesicles appear clear in electron micrographs. Made in the axon terminal by enzymes shipped down by slow axonal transport from the soma.


  2. CamKIIa kinase that phosphorylates synapsin and causes it to let go of the synaptic vesicles it is holding in the reserve pool


  3. small clear-core vesiclePackage neuropeptides. These vesicles are much larger in size than small clear-core vesicles. Made in the soma and shipped down to the terminal via fast axonal transport.


  4. Neurotransmitterschemical agents acting as messengers between the communicating neurons. Released from vesicle when the is a large Ca++ influx into the cell. How many are released depends on how much Ca++ enters the terminal.


  5. Gap JunctionsMake electrical synapses possible. Consists of hexameric subunits made up of subunits called connexons.