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5 Written questions

5 Matching questions

  1. large dense-core vesicles
  2. acetylcholine (ACh)
  3. Electrical synapses
  4. hsc-70
  5. end plates
  1. a with the aid of auxilin, this removes the clathrin coating so that the vesicle can move onto other phases of recycling
  2. b Package neuropeptides. These vesicles are much larger in size than small clear-core vesicles. Made in the soma and shipped down to the terminal via fast axonal transport.
  3. c A neurotransmitter found primarily at neuromuscular junctions of the striated muscles and in the visceral motor system. Involved in muscle contraction and heart rate increases.
  4. d neuromuscular junctions when synapses from the pre-synaptic axon elaborate and appear in a saucer-like shape on the muscle fiber
  5. e Work by allowing ionic current to flow PASSIVELY through the gap junction pores from one neuron to the next. Very fast transmission.

5 Multiple choice questions

  1. Involved in priming synaptic vesicles for release. Work by regulating the assembly of SNARE proteins.
  2. a V-SNARE protein that binds to the synaptic vesicle before exocytosis
  3. Vesicles that contain small molecule neurotransmitters. These vesicles appear clear in electron micrographs. Made in the axon terminal by enzymes shipped down by slow axonal transport from the soma.
  4. a SNARE protein on the surface of the synaptic vesicle. Binds Ca++ at concentrations similar to those required to trigger vesicle fusion, basically allowing it to act as a Ca++ sensor and triggering fusion.
  5. partially blocks post synaptic ACh receptors when placed in the extracellular medium. Used to study EPPs and MEPPs.

5 True/False questions

  1. synapsina protein that causes the final pinching-off of the membrane that completes the production of coated vesicles in the synaptic vesicle cycle.


  2. dynaminreversibly binds to synaptic vesicles and may cross link vesicle to actin filaments in the cytoskeleton to keep the vesicles tethered within the reserve pool.


  3. Gap JunctionsMake electrical synapses possible. Consists of hexameric subunits made up of subunits called connexons.


  4. synaptic vesicle cyclerecycling process for synaptic vesicle. Process takes about 1 minute.


  5. syntaxin and SNAP-25T-SNARE proteins embedded to the pre-synapatic membrane; attach to synaptic vesicles for vesicle fusion


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