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Chabner's Language of Medicine, 9th edition. Pathology for Chapter 16- Skin/Integumentary system

basal cell carcinoma

malignant tumor of the basal cell layer of the epidermis

squamous cell carcinoma

malignant tumor of the squamous epithelial cells in the epidermis

malignant melanoma

Cancerous growth composed of melanocytes; due to intense exposure to sunlight


increased growth of cells in the keratin layer of the epidermis caused by pressure or friction


hypertrophied, thickened scar developing after trauma or surgical incision


thickened and rough lesion of the epidermis; associated with aging or skin damage


absence of hair from areas where it normally grows

ecchymosis, ecchymoses

Bluish-purplish mark (bruise) on the skin.

petechia, petechiae

small, pinpoint hemorrhage



urticaria (hives)

acute allergic reaction in which red, round wheals develop on the skin


chronic papular and pustular eruption of the skin with increased production of sebum


Injury to tissues caused by heat contact.


diffuse, acute infection of the skin marked by local heat, redness, pain, and swelling


inflammatory skin disease with erythematous, papulovesicular lesions


death of tissue associated with decreased blood supply


Bacterial inflammatory skin disease characterized by vesicles, pustules, and crusted-over lesions.


chronic, recurrent dermatosis marked by itchy, scaly, red plaques covered by silvery gray scales


contagious, parasitic infection of the skin with intense pruritus


loss of pigment (depigmentation) in areas of the skin (milk-white patches)


An area of abnormal tissue anywhere on or in the body; may be caused by disease or trauma.


Collection of dried serum & cellular debris;scab; a common skin lesion


thick-walled, closed sac or pouch containing fluid or semisolid material; a common skin lesion


wearing away or loss of the epidermis; a common skin lesion


Groove or crack-like sore; a common skin lesion


flat lesion measuring less than 1 cm in diameter; a common skin lesion


solid, round or oval elevated lesion more than 1 cm in diameter; a common skin lesion


Small (less than 1 cm in diameter), solid elevation of the skin (pimples); a common skin lesion


growth extending from the surface of mucous membrane; a common skin lesion


papule containing pus; a common skin lesion


open sore on skin or mucous membranes (deeper than an erosion); a common skin lesion


small collection (papule) of clear fluid (serum); blister; a common skin lesion


smooth, edematous (swollen) papule or plaque that is redder or paler than the surrounding skin; a common skin lesion

first-degree burns

superficial epidermal lesions, erythema, hyperesthesia, and no blisters

second-degree burns (partial-thickness burn injury)

epidermal and dermal lesions, erythema, blisters, and hyperesthesia

third-degree burns (full-thickness burn injury)

Epidermal and dermis are destroyed (necrosis of skin), and subcutaneous layer is damaged, leaving charred, white tissue.

exanthematous viral diseases

Rash (exanthem) of the skin due to a viral infection; ex) rubella (German measles), rubeola (measles), and varicella (chickenpox)


chronic progressive disease of the skin and internal organs with hardening and shrinking of connective tissue

systemic lupus erythematosus (SLE)

chronic autoimmune inflammatory disease of collagen in skin, joints, and internal organs


infection of the skin caused by a fungus


white, thickened patches on mucous membrane tissue of the tongue or cheek

nevus, nevi

pigmented lesion of the skin


epidermal growth (wart) caused by a virus

Kaposi sarcoma

malignant, vascular, neoplastic growth characterized by cutaneous nodules

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