The hepatic portal vein (HPV) is the main channel of the portal venous system. It is formed anterior to the IVC and posterior to the neck of the pancreas (close to the level of the L1 vertebra) by the union of the superior mesenteric and splenic veins. .Although the HPV is a large vessel; it runs a short course to enter the liver. As it approaches the porta hepatis, the hepatic portal vein divides into right and left branches (enters two lobes). The hepatic portal vein collects blood with reduced oxygenation but rich in nutrients from the abdominal part of the digestive tract (intestine), including the gallbladder, pancreas, and spleen, and carries it to the liver. Streaming of the blood ﬂow is said to occur in which blood from the splenic vein, carrying the products of RBC breakdown from the spleen, passes mostly to the left liver. Blood from the SMV, rich in absorbed nutrients from the intestines, passes mostly to the right liver. Within the liver, the hepatic vein branches are distributed in a segmental pattern and end in expanded capillaries, the venous sinusoids of the liver.