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40 terms

Ch 13 Viruses

Tortora
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Viruses
Filterable agents, only visible through electron microscope
Viruses
Obligatory intra-cellular parasites
virion
complete virus
composition
nucleic acid protected by protein coat, double or single stranded, capsid, spikes
classifications
phenotypic characteristics, such as morphology, nucleic acid type, mode of replication, host organisms, and the type of disease they cause
host range of virus
range of cell types a virus can attack
taxonomy
families by nucleic acid type, morphology,
grown
in living animal, embryonated egg, or cell cultures
cytopathic effects
effects of virus on cell
how multiplication occurs
attachment, penetration (endocytosis or fusion), uncoating (virus removes capsid), reproduction, maturation, release
retrovirus
RNA virus that contain retroviral RNA
prion
infectious protein that causes spongy-form encephalopathies (mad cow disease, Kreutz-felt Jachob disease, sheep scraping), caused by cellular prion protein to scrapy proteins
viroid
short pieces of enveloped RNA with no viral coat that infect plant cells
envelope
combination of protein, carbohydrate, and covering virus
provirus
viral DNA integrated into host's DNA
virus obtains an envelope
budding
RNA viruses multiply where
cytoplasm
DNA
reverse transcriptase virus DNA incorporated where
HIV
does not make other animals than humans sick
all viruses have
capsid
bacteriophage
virus that infects bacteria
Parvoviridae
cause fetal death, gastroenteritis, SINGLE STRAND DNA
DOUBLE STRAND DNA
HAPP: herpesviridae, adenoviridae, papoviridae, poxviridae
Herpesviridae
fever blisters, chickenpox, DOUBLE STRAND DNA
Adenoviridae
respiratory infections, DOUBLE STRAND DNA
Papovaviridae
cause tumors, warts, cancer, DOUBLE STRAND DNA
Poxviridae
smallpox, cowpox, DOUBLE STRAND DNA
sense STRAND RNA
PiT
Picornaviridae
polio, common cold, sense STRAND RNA
Togaviridae
arthropod transmitted viruses, sense STRAND RNA
Antisense strand RNA
PORF: paramyxoviridae, orthomyxoviridae, rhabdoviridae, filoviridae
Paramyxoviridae
cause mumps, antisense strand RNA
Orthomyxoviridae
Influenza, antisense strand RNA
Rhabdoviridae
rabies virus, antisense strand RNA
Filoviridae
helical viruses; ebola, antisense strand RNA
Retroviridae
HIV and tumor viruses, two strands of RNA
Reoviridae
mild respiratory infections, gastroenteritis, double strand RNA
viral multiplication
APUB MR., attachment, penetration, uncoating, biosynthesis, maturation, release
prion disease
Creutzfeldth-Jakob,
Distinguish cancer cells
Undergo mitosis more rapidly- drug therapy targets "rapidly growing" cells; Not controlled by "contact inhibition;" Undergo "dedifferentiation", revert back to a form of embryonic cells, tend to be less "round" in shape and have more chromosomal abnormalities