False - just smokersT/F
everyone should get screened for lung cancer..BRAF
ALK
PD-L1
EGFR
These are actionableWhat biomarkers are associated with lung cancer?PD-L1: Pembrolizumab / Nivolumab
EGFR: Osimertibin / Erlotinib
ALK: Alectinib
BRAF: Dabrafenib / trametinib
VEGF: BevacizumabWhat drugs are for which biomarker?
PD-L1:
EGFR:
ALK:
BRAF:
VEGF:elevated LDH is associated with poor survivalWhat is associated with poor prognosis?Stage I-III (Limited Stage)
chemotherapy + RadiationWhat SCLC do we try to treat for a curative intent?Cisplatin or Carboplatin + etoposideWhat is the standard of care for limited stage SCLC?palliation, prolong life
can do chemotherapyWhat are the goals of extensive stage SCLC?Carboplatin + etoposide + atezolizumabWhat is the standard of care for extensive stage SCLC?≤ 6 months since therapy = use new drugs
> 6 months since therapy = use same drugsWhat do we do for patients that relapse?- smoking cessation
- routine follow-up
- supportive care
PCI for patients with good response to initial therapyWhat are some additional considerations for treatment?Stage I-III = surgeryWhat do we do for NSCLC treatment?Cisplatin + something elseIf chemotherapy is decided to be done for NSCLC...what is used?if no disease progression on initial therapy = use at least 1 drug from initial regimen / or switch
if failed initial therapy = re-evaluate treatmentFor maintenance therapy what do we do?smoking cessation
f-up q 3-6 months with chest CT
immunizations
wellness
pain management
N/VWhat is done for surveillance and supportive care?