4. Macrolides (Antimicrobials) - Pharmocology Final Exam

are macrolides bacteriostatic or bactericidal?

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are macrolides bacteriostatic or bactericidal?

name three macrolides pertinent to dentistry

erythromycin

clarithromycin (Biaxin)

azithromycin (Zithromax)

fidaxomicin (Dificid) is an

oral macrolide antibiotic that treats C. difficile infection

what drug is oral macrolide antibiotic that treats C. difficile infection?

fidaxomicin (Dificid)

fidaxomicin (Dificid) NOT absorbed orally and is not used for what?

NOT used for dental infection

erythromycin T1/2 is and administrated

1.5 hours and 4 times daily (q.i.d)

erythromycin and clarithromycin are inhibit by CYP3A4, may increase concentrations of:

benzodiazepines

erythromycin and azithromycin pregnancy class

clarithromycin has a longer T 1/2 and is can be administrated

twice daily (b.i.d) dosing or once daily (q.d)

clarithromycin pregnancy class