for moderate to severe chronic periodontitis:sub-antimicrobial doses of doxycycline 20 mg (Periostat)
-Periostat® 20 mg b.i.d. following scaling and root planing may be administered for up to 9 months
locally delivered 10% doxycycline hyclate gel (Atridox)
locally delivered minocycline 1 mg microspheres (Arestin)
