On July 5, an 11-year-old girl complained of pain in the knuckles of her left hand. During July 6-7, she had increasing pain that extended up to the left shoulder. A throat culture was obtained, and amoxicillin was prescribed. On July 9, she had difficulty walking and hallucinations. The throat culture was positive for Streptococcus pyogenes. She was treated with ceftriaxone. On July 11, she was hospitalized with a temperature of 40.7°C, and she could not drink. She developed respiratory distress and tachycardia; she died from cardiac arrest. Fluorescent-antibody testing of brain tissue revealed inclusions in the brain stem.
44) In Situation 22.1, the antibiotics did not cure her disease because the pathogen was
A) A virus.
B) Already growing in her brain.
C) Part of her normal microbiota.
D) Protected by the bloodbrain barrier.
E) Resistant to antibiotics.