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clinical chemistry gonadal and reproductive function

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what is a precursor to hormones
cholesterol
what is the main ovarian estrogen
estradiol
when do FSH and LSH peak in the female cycle
1-2 days before ovulation
what hormone stimulates testosterone secretion
leutenizing hormone
when does HCG peak during pregnancy
8-10 week after conception
what is produced in the adrenal gland and is a precursor to estradiol
DHES
what hormone do testes produce
testosterone
what hormone does the placenta make
HCG
what hormones do the ovaries make
estrogen and progesterone
name 2 tropic hormones made in the adrenal cortex
LH and FSH
what does LH stimulate in females
corpus leutium
what hormone does progesterone parallele
LH
when does FSH rise in a female cycle
at the beginning of the cycle when the egg is spit out
what are the 2 phases of the female cycle
follicular phase
luteal phase
in which phase, follicular or luteal, is the ovum released in
luteal phase
is a pregnancy test qualitative or quantitative
can be both
what type of pregnancy test is performed before surgery
quantitative
what type of test are most home pregnancy tests
qualitative
what syndrome can LOW alpha fetal protein indicate
downs syndrome
what condition can HIGH alpha fetal protein indicate
spinal bifita
where is a fetal screen done
in utero
what are the 2 most common causes of HDN
ABO and RH incompatibilities
if a pregnant woman is RH-, at what point during pregnancy is she given antinatal
27 weeks
if baby is born Rh + and mom is Rh-, when does mom receive her second dose of antinatal
at 72 hrs after birth
where does erythroblastic fatalis take place
in utero
when does HDN occur
after baby is born
what causes kernicterus and what are the affects of it
it's bili on the brain from hemolysis and can cause mental retardation
at what absorbance is amniotic fluid tested when assessing the level of hemolysis
450
list the zones of hemolysis levels in order from least to most severe in a Liley chart
zone 1, zone 2 and zone 3
what is the most common cause of newborn death
respiratory distress
why perform a fetal lung maturity test
to see how viable the lungs are
name the alvioli coating that keeps them from collapsing during the breathing process
surfactant
name the 3 lung phospholipids tested for presence of surfactant
phosphatidyglycerol
lecithin- most in amount
sphingomyelin
at 34-36 weeks of pregnancy, what happens to lecithin and sphingomyelin levels
lecithin rises and spingomyelin decreases
when determining the LS ration, what is the over/under number that helps determine the maturity of the lungs
2
with what technique is phosphatidylglycerol tested
thin layer chromatography or latex agglutination
what does lack of phosphatidylglycerol in the mom indicated if the mom is diabetic
a high risk of RDS for the infant
blood and muconium does not affect what test
phosphatidylglycerol test
what is a shake test and how is it performed
add amniotic fluid and ethanol to tube and shake.
if foam stays for 15 minutes, lungs are deemed mature
name the viscosity test used to check for fetal lung maturity
fluorescent polarization
-don't spin or use contaminated specimen
when should a fetal lung maturity test be done in the course of gestation
18 weeks