7489 Week 3, Day 1 Objectives (LEE)

Define osmolality.

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Define osmolality.

- the total number of particles of solute per 1 kilogram of solvent
- serum osmolality = 2[Na] + (BUN/2.8) + (glucose/18)

Define tonicity.

- describes solutes in solution that cannot cross the semi-permeable membrane
- hypotonic: water diffuses inward
- hypertonic: water diffuses outward
- isotonic: no net change in water movement

Describe fluid compartments in a body and distribution of total body water.

- total body water (42 L)
- intracellular fluid (28 L; 2/3 of TBW)
- extracellular fluid (14 L; 1/3 of TBW)

ICF:
- K⁺
- protein
- PO₄⁻³

ECF:
- interstitial fluid (10.5 L; 3/4 of ECF; Na⁺ and Cl⁻)
- intravascular fluid (3.5 L; 1/4 of ECF; RBCs and plasma)

0.9% NS contains _____ mEq/L of Na in one-liter bag.

Identify the tonicity of the following solution:

0.9%NS

Identify the tonicity of the following solution:

0.45%NS

Identify the tonicity of the following solution:

0.45%NS/D5W

Identify the tonicity of the following solution:

0.9%NS/D5W

Identify the tonicity of the following solution:

D5W

Identify the tonicity of the following solution:

5% albumin