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Pharm: Penicillins and Cephalosporins
Terms in this set (66)
Single-celled organisms lacking a true nucleus and nuclear membrane.
Classifications of bacteria based on their shape
Classifications of bacteria based on their cell-wall permeability
(1) Gram-positive (thin)
(2) Gram-negative (thicker)
The enzyme that many bacteria produce that destroys beta-lactam antibiotics such as penicillins and cephalosporins.
inhibit bacterial growth or kill bacteria
drugs that inhibit the growth of bacteria
drugs that kill backteria
Five mechanisms of antibacterial action
(1) inhibition of bacterial cell-wall synthesis
(2) alteration of membrane permeability
(3) inhibition of protein synthesis
(4) inhibition of the synthesis of bacterial ribonucleic acid (RNA) and deoxyribonucleic acid (DNA)
(5) interference with metabolism within the cell
Factors that influence the body's ability to fight infection
(4) white blood cells (WBCs)
(5) organ function
What population has less resistance to infection?
Older adults and undernourished individuals
Occurs without previous exposure to the antibacterial drug.
Example: Pseudomonas aeruginosa is inherently resistant to penicillin G.
Repeated exposures have caused this organism to evolve and become resistance to the antibiotic.
Example: MRSA, VREF, and VRSA
Developing a ________ ________ is another way to combat bacteria and lessen the need for antibiotics.
What is one of the main reasons that antibiotic resistance has increased?
Examples: (1) antibiotics are taken unnecessarily, or (2) taken incorrectly
Occur between antibacterial drugs that have similar actions, such as penicillins and cephalosporins.
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