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OC - Intro

STUDY
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How many people are diagnosed with head and neck cancer every year?
40,000
What is a Trojan peptide?
A vaccine that has been developed for Phase I clinical testing to treat squamous cell carcinoma of the head and neck
What is the Trojan peptide made out of?
HPV 16
MAGE A3
What are the six hallmarks of cancer?
Growht signal autonomy
Evasion of growth inhibitory signals
Evasion of apoptosis
Unlimited replicative potential
Angiogenesis
Invasion and Metastasis
How does cancer kill?
Organ failure
Obstruction of gastrointestinal tract, ducts and hollow organs
Cachexia - Extreme weight loss, emaciation similar to anorexia
Infection