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Terms in this set (82)
Neuro defects (myelination) caused by defective oxidation of very long chain fattys acids or branching FAs at odd carbons
Thrombosis prevention trt for angina if pt is allergic to aspirin
salivation, lacrimation, diaphoresis, urinary incontinence, diarrhea, emesis, miosis, bradycardia
Imcomplete obliteration of processus vaginalis
Bigger- indirect inguinal hernia
Sabin (live) vaccine is better than Salk (killed) vaccine in what way?
INC mucosal IgA production
Expression of hostile feelings in a non-confrontational manner
What lies just in front of the midportion of the esophagus?
Involuntary head bobbing caused by a cardiac problem
Widened pulse pressure due to aortic regurge
Why doesn't skeletal muscle respond to Ca channel blockers like cardiac and smooth muscle?
It doesn't need extracellular Ca
Vag problem that smells like fish, clue cells
BV (Gardnerella vaginalis)
Only HIV protein that is glycosylated and then cleaved
env (gp120 and gp41)
Mediate viral fusion to host cell
Accessory AV conduction pathway
Wolff Parkinson White Syndome
Shortened PR, delta wave, widened QRS
Dietary restriction for pts w problems in urea cycle (ie. transport of ornithine)
Too litte = impaired growth and development
To much = excess NH3 accumulation and CNS dysfunction
INC ACTH that is suppressed by high dose dexamethasone
What are we worried about in a pt w UC who presents w abd pain, distension, fever, diarrhea and signs of shock?
Toxic megacolon (do abd x-ray)
Trt for oropharyngeal candidiasis
MCC of malignant otitis externa
Pseudamonas (non-lactose fermenting, oxidase+, motile, G- rod)
What causes the granulomas in sarcoidosis?
Th1cells, IL-2 and IFN-gamma
Most important virulence factor in S. epi?
Synthesis of extracellular polysaccharide matrix (biofilms)
Baby- deafness, cataracts, PDA
Hyperparathyroidism, pituitary tumor, pancreatic tumor
Another name for 5th disease
Mycobacteria lost acid fastness and stop proliferating. Whats the drug?
Works on mycolic acids
Where is most of the water reabsorbed in the nephron?
Proximal Tubule (60%, passive)
How does N-acetlycysteine work in CF?
cleaves disulfide bonds w mucus glycoproteins, thus loosening thick sputum
1/r1 + 1/r2 + 1/rn'
Trt for urge incontinence
Anti-muscarinic (M3; oxybutynin)
HTN crisis w ingestion of tyrosine
Drug Reation, Eosinophilia, Systemic Symptoms
DRESS Syndrome (anticonvulsants and allopurinol)
Fever, LAN, facial edema, rash
MC heart problem in Turners Syndrome
Bicuspid aortic valve
Before alanine can be converted to glucose, amino group is transferred to what?
Particles in terminal bronchioles. How does the body take care of this?
Mucociliary clearance (ciliated cells)
Normocytic anemia, osteopenia, hypercalcemia, INC infections, AL amyloid, renal failure
Multiple Myeloma (>30% plasma cells in bone marrow sample)
Secretory diarrhea, lots of mucus, cauliflower like mass in sigmoid colon
Substrate level phosphrylation step of TCA cycle
Succinyl-CoA to Succinate
Rucurrent lobar hemorrhages in an elderly pt
Cerebra amyloid angiopathy
Positive babinski, spasticity, muscle weakness, hyperreflexia
Most important prognostic factor in PSGN
Athlete w erythrocytosis
Iron deficiency anemia, what must be ruled out?
Blood loss (think GI)
Major prognostic factor for transitional cell carcinoma
Tumor penetration into the bladder wall
MCC of Vfib in pts < 30 years old
Malignant ovarian epithelial tumor
Splenic problems in SC anemia caused by
Substrate concentration changes along the proximal tubule
INC: PAH, creatinine, inulin, urea
DECBicarv, glucose, AAs
Hypertrophy of calf in Duchennes is actually what?
Fibrofatty muscle replacement
What mtochondrial enzyme activates caspases in the intrinsic apoptotic pathway?
Optic neuritis, INO, sensory deficits. Gets worse w heat
Effect of COPD on residual volume
Initial empiric therapy for Staph epi after mitral valve replacement
Vancomycin, if proven to be methacillin sensitive, switch to nafcillin of oxacillin
Calcium kidney stone. What are the serum and urine levels of Ca?
Pathogenesis of alcohol induced hepatic steatosis
DEC in FFA oxidation secondary to excess NADH
Opioid effect that does not show tolerance
Constipation and pupil miosis
Site of rRNA synthesis
Rapidly progressive dementia and myoclonic jerks; vacuoles in gray matter of brain
What type of E coli does not ferment sorbitol?
Shiga like toxin- inactivates ribosomal subunits (60S)
Fetus blood supply from placenta
Umbilical vein through the ductus venosus to the IVC
Sorbitol is broken down into what?
Seen most in seminal vesicles
There are 3 dopaminergic pathways
16S rRNA subunit
In 30S subunit; contains the opposite of the Shine Delgarno sequence to help initiate protein translation
INC CO and INC venous return caused by
First thing to check if you suspect temporal arteritis
Go aheasd and trt w corticosteroids to prevent vision loss
Trt for combined absence and tonic-clonic seizures
What artery supplies blood to the diaphragmatic surface of the heart?
High fever, watery diarrhea, HA, mildly productive cough. Gram stain shows PMNs but no bugs. Smoker.
Estrogen agonist in bone, heart and lipoproteins
Antagonist in breasts and uterus
No peptidoglycan or no cell wall means what meds are ineffective?
Penicillins and cephalosporins
Change in base pairs not in a multiple of 3
Trt for enterobiasis
Albendazole (worms are "bendy")
Malignant hyperthermia, severe hyperkalemia, HR problems
SE of succinylcholine
Costa rican man w achalasia
Trt for acute intermittent porphyria
IV glucose or heme preparations (DEC ALA synthetase activity)
Broutons pts have problems w what bugs?
pyogenic bacteria, enteroviruses, Giardia
Why is there hyperlipidemia in mephropathy?
INC production of proteins in liver to compensate for DEC albumin (INC lipoprotein synthesis)
Intravaginal injection near ischial spine
Pudendal nerve block
Baby w jaundice, muscle rigidity, lethargy and seizures
Most important prognostic indicator in melanoma
Negative test result chances of not having the disease
Respiratory distress, confusion and upper body petechial rash after long bone fractures
DEC RBC, hematocrit, platelet count
INC bleeding time, LDH, BUN, creatinine
INC insulin, proinsulin and c-peptide levels
Insulinoma or sulfonylurea/meglitinide use
Naloxone works most at what receptor
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