Has sedative effects. Use w/ caution, especially driving, heavy machinery, and other sedatives like alcohol.
• Prolonged use may cause headache, nervousness, or cardiac abnormalities.
As with benzodiazepines, there may be a risk of paradoxical excitation and physical dependence.
• In theory, valerian can potentiate the actions of other drugs with CNSdepressant actions. Among these are alcohol, benzodiazepines, barbiturates, opioids, antihistamines, and centrally acting skeletal muscle relaxants. These combinations should be used with caution.. p. 1271).