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5 Written questions

5 Multiple choice questions

  1. Inactivated RSK2.
    ATF4 isn't turned on
    can't import AA or fully differentiate osteoblasts
    treated with high protein diet
  2. Via sox9.
    Haploinsufficiency leads to dwarfism.
  3. From monocytes
    Osteoblasts secrete both OPG and RANKL
    OPG binds and inhibits RANKL
    RANKL causes osteoclast maturation
  4. VEGF
    Osteoclasts are brought in with blood vessels (since they are monocytes after all)
    Osteoblasts also migrate from the bone collar to trabeculae
  5. Patterning ~> Skeletogenesis ~> Homeostasis
    Dyostoses Dysplasia
    Lethal Lethal 50% population problems

4 True/False questions

  1. neurofibromatosisover-activated RSK2.
    Too much ATF4 ~> osteoclacin ~> too many osteoblasts

          

  2. Proliferation of chrondrocytesVia sox9.
    Haploinsufficiency leads to dwarfism.

          

  3. Basic bone cell typesChondrocyte, osteoblast, osteoclast
    Growth Formation Resorption

          

  4. Cleidocranial dysplasiaover-activated RSK2.
    Too much ATF4 ~> osteoclacin ~> too many osteoblasts