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55 terms

Pharmacology

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Asthma paradox
Unexplained increase in asthma related deathsbdespite advances in treatment of disease
Side effects beta 2
Palpitations,tachycardia,tremors
Maintenance drug
Salmeterol Serevent
Pro drug
bitolterol Tornalate converts to colterol to make active
Isoetharine
Bronkosol
isoproterenol
Isuprel
isoproterenol Isuprel
Shorter duration due to COMT breakdown catecholamine
Has Synthetic Used for upper airway swelling
Racemic Epinepherine
Micronephrin Vaporefin
Racemic epinepherine trade names
albuterol
Saligenin class
pirbuterol Maxair
Saligenin
Salmeterol
MaintenanCe drug
Saligenin class maintenance drug
salmeterol Serevent
levalbuterol Xopenex
Saligenin class
metraproterenol
Alupent
Metrapel Alputent metraproterenol
Rescorinol class
terbutaline
Brethine Brethaire Bricanyl
Rescorinol class
terbutaline what class
Prodrug
Tornalate Bitolterol
dopamine Intropin
Used to treat cardiac arrest
Stimulation of beta 2
Inhibits inflammatory mediator release,and degranulation of mast cells
Heat air light
Catecholamines are inactivated by
Pink
Catecholamines may cause sputum to be
MAO COMT
Rescorinol agents don't have .... And .... Inactivation
Resorcinol agents
Have a longer duration up to six hours
terbutaline albuterol
Non catecholamine with greatest B2 selectivity
Sub q epinepherine epinepherine
Which drug has a rapid onset short duration for immediate bronchodilators
10-20 mcg
What is the optimum serum level for max bronchodilation in adults of a xanthine (second or third line agents)
Tea caffenine
Are second or third line agents used tobtreat COPD
Xanthines or methyl xanthines
Relax muscles given through IV
Atrovent
Which has less side effects Atrovent or atropine
Anticholinergics
Which are more tent to bronchodilator in bronchitis emphysema
Iratropium bromide and albuterol
Which mixed drug is muscarinic and B2 and available in MDI form
tiotropium bromide Spiriva
Which quarternary is considered maintenance drug and causes dry mouth
Atrovent ipatropium bromide
Which muscarinic Quartenary is preferred becausebit does not cross blood brain barrier or lipid membranes
Ipratropium bromide Atrovent and Spiriva tiotropium bromide
Two drugsvQuaternary subclass
Quaternary
Dosent distribute thru body when inhaled
Tertiary small dose
Minor slow hr
Lg dose Tertiary class will
Increase hr
Tertiary treats
Bradycardia during cardiac arrest
Tertiary class atropine Dey dose
Reduces mucous clearance,blocks hyper secretions,relax airway smooth muscle
Increased
Dietary has a ....effect with each dose
Cross blood brain barrier
Tertiary ammonium compounds are distributed throughout the body and "................to cause CNS changes
Basal tone
Parasympathetic branch maintains..... ...... In bronchial smooth muscle
CBABE
Cystic fibrosis,bronchitis,asthma,bronchiectasis,emphysema
isoetharine Bronkosol
Used pre and post asthma study to prevent bronchospasm from other inhaled drugs
racemic epinephrine Micronephrine Vaponephrine
Catecholamine Synthetic drug used in cases of stridor or upper airway swelling
Epinepherine
Used as cardiac stimulant has fast onset with short duration
Isoproterenol isoetharine racemic epinepherine
Catecholamines
biolterol Tornalate
Converts to colterol to make active
Rescorinol agents
Can be taken orally and won't be broken down used for maintenance therapy due to long duration
Xanthines
Relaxes Vascular smooth muscle uterine
Treats asthma copd
Xanthines
Maintenance drug stimulate CNS
Xanthine theophylline theobromine aminophylline
Combivent and Duoneb
Becomes muscarinic and B2 is receptor site