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Chapter 11: Overview of Energy Metabolism

STUDY
PLAY
What organ doesn´t change his metabolism in the Well fed and Starvation state?
RBC: use glucose for both. Via Glycolisis produces ATP.
(pag. 164)
ALT: What does do this enzyme?
Transform Alanine to Pyruvate (pag. 163)
ALT needs Vitamin B6 to generate his function (pag. 148)
What is TRANSKETOLASE?
Is an enzyme that needs Thiamine (Vitamin B1) for it´s normal function and is used to measure Thiamine deficiency. You have to measure Transketolase activity in RBC (pag.147)
Most common cause of Thiamine (Vitamin B1) deficiency?
Alcoholism (pag. 147)
Which is the relation between Thiamine (Vitamin B1) and Hypoglycemia?
In Thiamine (Vitamin B1) deficiency the enzyme PYRUVATE DEHYDROGENASE is not going to work so you can´t transform Pyruvate to Acetyl CoA to generate energy. (pag. 147 and 162)