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21 terms

Cardimyopathy & Heart Failure

Dr. Nine - November 11, 2011 Semester 3, Mini 3
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What is the most common form of cardiomyopathy?
dilated cardiomyopathy
What are underlying associations with dilated cardiomyopathy?
alcohol, obesity, pregnancy, sleep apnea
What are the histologic findings in dilated cardiomyopathy?
myofiber hypertrophy and disarray
"lacy" interstitial fibrosis
Genetic defects in what proteins can cause dilated cardiomyopathy?
dystrophin, desmin
What is the treatment for dilated cardiomyopathy besides heart transplant?
pacemaker
What type of cardiomyopathy can occur during or up to 6 months after pregnancy?
dilated cardiomyopathy
What type of cardiomyopathy has a 100% genetic cause and prominent left ventricle?
hypertrophic cardiomyopathy
Idiopathic hypertrophic subaortic stenosis is associated with what type of cardiomyopathy?
hypertrophic
Hypertrophic cardiomyopathy is associated with mutations in what protein?
sarcomeric myosin heavy chain, light chain
What type of cardiomyopathy is prominent in young athletes?
hypertrophic
What are the main causes of restrictive cardiomyopathy?
cardiac amyloidosis and endocardial fibroelastosis
What is cardiac amyloidosis?
build up of abnormal fibril in the heart muscle
What cardiac problem is seen in multiple myeloma?
cardiac amyloidosis
What stains apple-green birefringence with congo red?
cardiac amyloidosis
What age group is effected by endocardial fibroelastosis?
infants and young children
What is the hallmark feature of arrhythmogenic right ventricular cardiomyopathy?
fatty infiltration and fibrosis of right ventricular myocardium
What are the clinical features of arrhythmogenic right ventricular cardiomyopathy?
rare, autosomal dominant, can cause sudden death due to arrhythmia, right heart failure, young pts
What does left heart failure lead to?
pulmonary edema and congestion
In what type of heart failure are "heart failure cells" found?
left
What is "nutmeg" liver associated with?
right heart failure
What is right heart failure called when it occurs alone?
cor pulmonale