-Amines or Amino Acid Derivatives -Peptide -Eicosanoid (in between hydrophilic and hydrophobic)
What are the two types of Hydrophobic hormones?
-Steroid (majority) -Thyroid
What are characteristics of Amines or Amino Acid Derivatives?
-Synthesized by decarboxylating (CO2) from ONLY 1 amino Acid -Stored in vesicles -STIMULUS causes release (What are the three types of Hydrophilic hormones?)
What are characteristics of Peptide Hormones?
-Polymers of amino acids (3 to 300+ amino acids) -Stored in vesicles -STIMULUS causes release (What are the three types of Hydrophilic hormones?)
What are characteristics of Eicosanoid Hormones?
-Derived from Arachidonic Acid -Work over short distances -Inactivate quickly -NOT stored -Stimulus causes secretion and synthesis -ARE NOT Amino Acid derivatives (What are the three types of Hydrophilic hormones?)
What is an example of an Amine or Amino Acid Derivative Hormone?
What are examples of Peptide Hormone?
What is an example of Eicosanoid Hormone?
What are characteristics of Steroid Hormones?
-Derived from CHOLESTEROL -NOT stored -Stimulus causes secretion and synthesis (What are the two types of Hydrophobic Hormones?)
What are characteristics of Thyroid Hormones?
-Synthesized by attaching Iodine to Tyrosine -NOT stored -Stimulus causes secretion and synthesis (What are the two types of Hydrophobic Hormones?)
What is an example of Steroid Hormone?
What is an example of Thyroid Hormones?
How are Hormones secreted?
-Secreted from specialized neuronal cells (neuroendocrine cells)
What occurs in Neuroendocrine cells?
-Conversion of electrochemical signal to hormonal signal -Stimulation by neurotransmitter (neuroendocrine) releases hormone into the blood stream
The Steroid Hormones in our body (estrogen, progesterone..) are all derived from?
Hormones are effective in what relative concentrations?
-Nanomolar to picomolar (10^-9 to 10^-12)
What is the Physiological concentration?
-the amount of hormone necessary to elicit a "normal" response
What is the Pharmacological concentration?
-the amount of hormone found when taken as a drug -may produce exaggeration of physiological effects (side effects) or non characteristic effects
What is the Pathological concentration?
-an abnormally high or low concentration of hormone produced by an endocrine gland -produces non-characteristic effects Example: (High Growth Hormone = 7 feet tall)
How do Hydrophilic Hormones transport or circulate?
-circulate free in blood plasma
How do Hydrophobic Hormones transport of circulate?
-circulate bound to transport protein -make lipid soluble proteins water soluble -retards degradation -provide temporary storage place