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Long Acting Bronchodilators
For maintenance, duration 12hrs, Often used in combination w/ Corticosteroids
Long Acting Bronchodilator Rx <ADVair>
Salmeterol (Serevent) + Fluticasone (a synthetic corticosteroid.)= Advair
a bronchodilator and corticosteroid combination used to treat and prevent the symptoms of asthma.
Clinical Indications for use of Xanthines
Considered the primary agent of choice for Apnea of Prematurity
two or more agents working on the same target organ, resulting in a product greater than the sum of its parts
Long -Acting Bronchodilators(12 hrs)
Serevent(Salmetrol) , Foradil(Formoterol), Brovana(Arformoterol)
Purpose of Mucus in physiology
effective lubricant, protective barrier, and sticky trap for foreign particles and microorganisms
Factors that slow mucus clearance
lung disease(COPD,CF), Airway drying, Narcotics, Airway Trauma, Cigarrette Smoking, Atmosphere pollutants
mucolytic,(mucomyst) may cause bronchospasm (use w/bronchdilator), limited shelf life (refrig)
Bronchoalveolar Lavage (BAL)
bronchoscope passed through mouth or nose into the lungs, a fluid is squirted into a small part of the lung and then recollected for examination.
Three Classifications of Antiinflammatory Agents
Corticosteroids, Leukotriene Antagonists, and Mast Cell Stabilizers
Angiotensin Converting Enzyme Inhibitors Mode of Action(ACE Inhibitors)
Blocks the conversion of Angiotensin I to Angiotension II
Mast Cell Stabilizers
inhibit the release of inflammatory chemicals from mast cells and make the airways less likely to narrow.
Combined Inhaled Medicines Defined
Bronchodilators that combine a controller inhaler and a quick relief inhaler, or combine 2 controller inhalers into one.
rapidly decreasing response to a drug following administration of initial doses
a, Subcutaneous, intramuscular, or intravenous method of administration; treatment by injection.
20% increase to heart rate over baseline
Considerations to stop treatment of SABA (Sign of Side Effect)
The most common Sympatholytic Agent (Drugs that inhibit the actions of the sympathetic nervous system by any mechanism)
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