disease of sheep, cattle, horses, goats, and swine.
Mostly contracted by handling of contaminated wool or hides (usually from the Mid-East
CUTANEOUS: Area of necrosis (a purple to black eschar) surrounded by erythema, with vesicular lesions, not prurulent. The eschar typically is painless; pain indicates secondary staphylococcal or streptococcal infection.
INHALATION: Within hours to a few days, symptoms or signs of overwhelming sepsis predominate.
GASTROINTESTINAL: Fever, diffuse abdominal pain, rebound abdominal tenderness, vomiting, constipation, and diarrhea occur 2-5 days after ingestion of meat contaminated with anthrax spores.
HALLMARK: Mediastinal widening due to hemorrhagic lymphadenitis
Most common cause of Pharyngitis: sore throat, n/v, enlarged tonsils, spots
-common complications include: Rheumatic Fever, Glomerulonephritis, sinusitis, otitis media, mastoiditis, peritonsilar abscess, suppuration of cervical lymph nodes
skin infections - impetigo, erysipelas, cellulitis, necrotizing fascitis
Erythema migrans, Bell's palsy, arthritis
most common tickborne disease in the United States and Europe
stage 1: Early Localized Infection: characterized by erythema migrans (and flu-like symptoms)
stage 2: Early Disseminated Infection: weeks to months later, Bell palsy or aseptic meningitis (with mild headache and neck stiffness), secondary skin lesions that are not associated with a tick bite and Malaise, fatigue, fever, headache (sometimes severe), neck pain, and generalized achiness are common with the skin lesions.
stage 3: Late Persistent Infection: months to years later, primarily manifests itself as musculoskeletal, neurologic, and skin disease. Arthritis (10%) and late manifestations and specifies whether disease is localized or disseminated.
fever, "unchanging murmur", musculoskeletal symptoms
petechiae, subungual "splinter" hemorrhages", osler nodes, janeway lesions, ,roth spots, strokes, hematuria, proteinuria