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Terms in this set (12)
used by bacteria to release signalling molecules
is cholera an example of an AB toxin?
give an example of a single chain AB toxin?
Diphtheria, cholera, tetanus and botulinum
how does diphtheriae work?
inactivates ELF by modifiying a histidine called diphthyramide to inhibit protein synthesis
how does v. cholerae work?
modifies G proteins that increase adenylate cyclase
how do C. Tetani and botulinum work?
tetani works by blocking release of inhibitory neurotransmitter and botulinum works by inhibiting ACH release
to what do superantigens bind?
external regions of the TCR and MHC2 molecules
what are molecules that bind iron with high affinity and steal it from host iron storage proteins?
what's the cool adherence method used by enteropathogenic E. Coli (EPEC)?
injects a receptor for bacterial adherence then uses it as a pedestal
Name five methods of evading phagocytosis
pili, biofilm, capsule (interferes with complement deposition/mimics host molecules), ihibition of phagocytosis (inject shit that messes up their ability to rearrange their cytoskeleton), killing of phagocytes by toxins
lyse the hose phagosome and replicate in the cytosol
give the example of the guy who toughs it out in the phagolysosome
coxiella (cox toughing it out)
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