NAME

Question types


Start with


Question limit

of 33 available terms

Advertisement
Print test

5 Written questions

5 Matching questions

  1. side effects of glycopeptide
  2. common macrolide agents
  3. side effects/adverse run of macrolide
  4. avelox
  5. Fluoroquinolones
  1. a -erthromycin (iv)
    -clarithromycin
    -azithromycin (long 1/2 life) (iv)
    -dirithromycin
  2. b -gi n/v/d/ abdominal cramping
    -allergic rn are rare
    -when combined with other hepatotoxic drugs leads to hepatotoxicity; usually reversible when the drug is discnt.
  3. c -more active against s. pneumoniae than levaquin is
  4. d -vanocomycin
    -s/e: nephrotoxicity, ototoxicity damage (8th cranial nerve) can be permanent or temp, chills, dizziness, fever, rash, n/v
  5. e -interferes with enzyme DNA gyrase- needed to synthesize bacterial DNA
    -bactericidal on gram + and -
    -mainly used for tx of UTI, bone, joint infect; bronchitis, pneumonia, gastroenteritis, gonorrhea
    -high tissue distribution
    -food/antacids slow absorption rate

5 Multiple choice questions

  1. -sub cat of macrolide
    -focus of vancomycin
    -bactericidal
    -used against drug-resistant s.aureus and cardiac surf prophylaxis w pt with PCN allergy
  2. - due to too rapid of an infusion of glycopeptide
    -red blotching of face/neck/chest
    -toxic not allergic rxn
    -no need to stop infusion, lower infusion rate
  3. -IM/IV
    -shot half life; given 3-4 days daily
    -excreted via urine
  4. -inhibits bacterial DNA synthesis by inhibiting the enzyme DNA gyrase
    -effect of oral hypoglycemics, theophylline and caffeine are increased with concurrent use of a Fluoroquinolones
    -peak con: 1-2 hrs
  5. may increase serum levels of:
    -theophyline
    -carbamazepine
    -warfarin
    -do not administer with antacids bc may increase peak levels of macrolide

5 True/False questions

  1. pharmacodynamics of macrocodes-readily absorbed from the GI tract; excretion in bile, feces, urine
    -only a small amy is excreted in urine, therefore renal insufficiency is not a contraindication for macrolide use

          

  2. common examples of Fluoroquinolones-cipro
    -levaquin
    -avelox

          

  3. ketolides-bacteriostatic; with high doses can be bactericidal
    -used as pen sub.; diff in structure of pen
    -broad spectrum
    -used to treat mild-moderate infection of reps tract, sinuses, gi tract, skin, soft tissue, impetigo and STI
    -PO, slow IV
    -e-mycin drug of choice for Legionnaires mycoplasmal pneumonia

          

  4. Tetracyclines-bacteriostatic
    -used in combination to treat h.pylori
    -resistance has increased in treatment of pneumococcal and gonococcal infections
    -orally use mainly
    -available in IV/IM- rare cause of pain
    -not to be taken with magnesium/aluminum antacid preparations, calcium containing products.- prevents absorption

          

  5. pharmcokinetics of Fluoroquinolones-inhibits bacterial DNA synthesis by inhibiting the enzyme DNA gyrase
    -effect of oral hypoglycemics, theophylline and caffeine are increased with concurrent use of a Fluoroquinolones
    -peak con: 1-2 hrs