NAME

Question types


Start with


Question limit

of 33 available terms

Advertisement Upgrade to remove ads
Print test

5 Written questions

5 Matching questions

  1. other pcn sub., along w macrocodes
  2. aminoglycosides
  3. macrolides
  4. pharmacodynamics of aminoglycosides
  5. intermediate acting Tetracyclines
  1. a -lincosamides
    -gylcopeptides
    -ketolides
  2. b -inhibits bacterial protein synthesis
    -gram - bact
    -reserved for serious infections
    -not absorbedvia GI tract; does not cross BBB
    -IM/IV only
    -gentamycin, tobramycin, amikacin, streptomycin
    -s/e: ototoxicity, nephrotoxicity, superinfection
    -peak levels drawn to monitor toxicity
    -troug levels to monitor maintenance of therapeutic drug levee
  3. c -bactericidal
    -preg cat. C
    -onset of action: immediate
    -peak action: 1-2 hrs
  4. d -PO only
    -declomycin
  5. e -bacteriostatic; with high doses can be bactericidal
    -used as pen sub.; diff in structure of pen
    -broad spectrum
    -used to treat mild-moderate infection of reps tract, sinuses, gi tract, skin, soft tissue, impetigo and STI
    -PO, slow IV
    -e-mycin drug of choice for Legionnaires mycoplasmal pneumonia

5 Multiple choice questions

  1. -PO only
    -Sumycin
  2. -IM/IV
    -shot half life; given 3-4 days daily
    -excreted via urine
  3. -increase risk with declomycin and long acting forms.
    -get sun-burnt 10x worse than average
  4. -well absorbed from GI tract
    -low protein binding effect
    -moderate half life: 6-8 hrs
    -excreted via urine
  5. -inhibits bacterial DNA synthesis by inhibiting the enzyme DNA gyrase
    -effect of oral hypoglycemics, theophylline and caffeine are increased with concurrent use of a Fluoroquinolones
    -peak con: 1-2 hrs

5 True/False questions

  1. ketolides-structurally related to macrocodes
    -ketek: (18+) treats mild to moderate CAP
    -adverse rxn: may lead to an exacerbation of myashenia gravis
    -many drug interactions

          

  2. pharmacodynamics of glycopeptides-oral: treats antibiotic associated pseudomembranous colitis due to c.diff
    -IV: treats severe infections due to MRSA; septicemia; bone, skin, lower reps tract infect that are resistant to other antibiotics
    -t-1/2 life: 6 hrs
    -excretion via urine

          

  3. Tetracyclines-bacteriostatic
    -used in combination to treat h.pylori
    -resistance has increased in treatment of pneumococcal and gonococcal infections
    -orally use mainly
    -available in IV/IM- rare cause of pain
    -not to be taken with magnesium/aluminum antacid preparations, calcium containing products.- prevents absorption

          

  4. side effects of glycopeptide-vanocomycin
    -s/e: nephrotoxicity, ototoxicity damage (8th cranial nerve) can be permanent or temp, chills, dizziness, fever, rash, n/v

          

  5. Fluoroquinolones-interferes with enzyme DNA gyrase- needed to synthesize bacterial DNA
    -bactericidal on gram + and -
    -mainly used for tx of UTI, bone, joint infect; bronchitis, pneumonia, gastroenteritis, gonorrhea
    -high tissue distribution
    -food/antacids slow absorption rate