NAME

Question types


Start with


Question limit

of 33 available terms

Advertisement Upgrade to remove ads
Print test

5 Written questions

5 Matching questions

  1. macrolides
  2. extended macrolides
  3. aminoglycosides
  4. Tetracyclines
  5. macrolide drug interactions
  1. a -all inhibit protein synthesis
    -clarithromycin: 2x a day (BID)
    -azitromycin: QD x 5 days; t-1/2= 50 hours
  2. b may increase serum levels of:
    -theophyline
    -carbamazepine
    -warfarin
    -do not administer with antacids bc may increase peak levels of macrolide
  3. c -inhibits bacterial protein synthesis
    -gram - bact
    -reserved for serious infections
    -not absorbedvia GI tract; does not cross BBB
    -IM/IV only
    -gentamycin, tobramycin, amikacin, streptomycin
    -s/e: ototoxicity, nephrotoxicity, superinfection
    -peak levels drawn to monitor toxicity
    -troug levels to monitor maintenance of therapeutic drug levee
  4. d -bacteriostatic
    -used in combination to treat h.pylori
    -resistance has increased in treatment of pneumococcal and gonococcal infections
    -orally use mainly
    -available in IV/IM- rare cause of pain
    -not to be taken with magnesium/aluminum antacid preparations, calcium containing products.- prevents absorption
  5. e -bacteriostatic; with high doses can be bactericidal
    -used as pen sub.; diff in structure of pen
    -broad spectrum
    -used to treat mild-moderate infection of reps tract, sinuses, gi tract, skin, soft tissue, impetigo and STI
    -PO, slow IV
    -e-mycin drug of choice for Legionnaires mycoplasmal pneumonia

5 Multiple choice questions

  1. -PO only
    -Sumycin
  2. -gi n/v/d/ abdominal cramping
    -allergic rn are rare
    -when combined with other hepatotoxic drugs leads to hepatotoxicity; usually reversible when the drug is discnt.
  3. -more active against s. pneumoniae than levaquin is
  4. -inhibits bacterial DNA synthesis by inhibiting the enzyme DNA gyrase
    -effect of oral hypoglycemics, theophylline and caffeine are increased with concurrent use of a Fluoroquinolones
    -peak con: 1-2 hrs
  5. -structurally related to macrocodes
    -ketek: (18+) treats mild to moderate CAP
    -adverse rxn: may lead to an exacerbation of myashenia gravis
    -many drug interactions

5 True/False questions

  1. long acting tetracyclines-PO only
    -Sumycin

          

  2. pharmacokinetics of macrolides-orally: absorption by GI tract
    -not affected by food intake
    -excreted through feces, urine
    -t-1/2: 10 hrs

          

  3. pharmacokinetics of glycopeptides-oral: treats antibiotic associated pseudomembranous colitis due to c.diff
    -IV: treats severe infections due to MRSA; septicemia; bone, skin, lower reps tract infect that are resistant to other antibiotics
    -t-1/2 life: 6 hrs
    -excretion via urine

          

  4. pharmacokinetics of ketolides-orally: absorption by GI tract
    -not affected by food intake
    -excreted through feces, urine
    -t-1/2: 10 hrs

          

  5. other pcn sub., along w macrocodes-lincosamides
    -gylcopeptides
    -ketolides