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REDUCED STATE. A coenzyme that easily cycles between oxidized and reduced states thus acting as an electron carrier
NAD+ (Nicotinamide adenine dinucleotide)
OXIDIZED STATE. A coenzyme that cycles between oxidized and reduced states, it acts as an electron carrier.
The totality of an organism's chemical reactions, consisting of catabolic and anabolic pathways, which manage the material and energy resources of the organism.
First Law of Thermodynamics
The principle of conservation of energy: energy can be transferred and transformed, but it cannot be created or destroyed.
Second Law of Thermodynamics
The principle stating that every energy transfer or transformations increases the entropy of the univers. Usable forms of energy are at least partially converted to heat.
A nonspontaneous chemical reaction, in which free energy is absorbed from the surroundings
ATP (adenosine Triphosphate)
An adenine-containing nucleoside triphosphate that releases free energy wen its phosphate bonds are hydrolyzed. this energy is used to drive endergonic reactions in cells.
A macromolecule serving as a catalyst, a chemical agent that increases the rate of reaction without being consumed by the reaction. Most of proteins.
Activation Energy (free energy of activation)
The amount of energy that reactants must absorb before a chemical reaction will start.
the specific region of an enzyme that binds the substrate and that forms the pocket in which catalysis occurs.
A chemical agent that selectively increases the rate of a reaction without being consumed by the reaction.
The action of an inhibitor such that once bound to a protein cannot dissociate
A series of chemical reactions catalyzed by enzymes and are connected by their intermediates.
The break down of complex molecules to form simpler ones, other with the release of energy.
The synthesis of complex molecules in living organisms from simpler ones together with the storage of energy.
The product of ATP dephophorylation via ATPase to release energy; can be converted to ATP by phophoylation.
Induced Fit Hypothesis
Caused by entry of the substrate, the change in shape of the active site of an enzyme so that it binds more snuggly to the substrate. "handshake"
Any nonprotein molecule or ion that is required for the proper functioning of an enzyme. they can be permanently bound to the active site or may bind loosely and reversely along with the substrate during catalysis.
A substrate that reduces the activity of an enzyme by entering the active site in place of the substrate whose structure it mimics.
A substance that reduces the activity of an enzyme by binding to a location remote from the active site, changing the enzyme's shape so that the active site no longer effectively catalyzes the conversion of substrate to product.
The binding of a regulatory molecule to a protein at one site that affects the function of the protein at a different site.
A method of metabolic control where the end product of a metabolic pathway acts as an inhibitor of an enzyme within that pathway.
A catabolic process that makes a limited amount of ATP from glucose without an electron transport chain and that produces a characteristic end product like ethyl alchol or lactic acid
An important intermediate in the krebs cycle which breaks down glucose into water and carbon dioxide when oxygen is present
Formed by the oxidaiton of malic acid in the krebs cycle and by transimation from aspartic acid. An important intermediate in the metabolism of carbohydrates.
A colorless, water-soluble organic liquid produced by the breakdown of carbohydrates and sugars during glycolysis.
A redox cofactor involved in several important reactions in metabolism, it converts between by accepting or donating electrons.
A catabolic pathway in which inorganic molecule other than oxygen accept electrons at the "Down hill" end of the electron transport chain
A catabolic process that makes a limited amount of ATP from glucose without an electron transport chain and that produces a characteristic end product like ethyl alcohol or lactic acid
Infolding of the inner membrane of a mitochondrion, which houses electron transport chains and molecules of the enzyme catalyzing the synthesis of ATP.
electron transport chain
A sequence of electron carrier molecules that shuttle electrons down a series of redox reaction that release energy used to make ATP
A catabolic pathway for organic molecules, using oxygen, as the final electron acceptor in an electron transport chain and ultimately producing ATP, MOst effiecent
Glycolsis followed by the reduction of pyruvate to ethyl alcohol, regenerating NAD+ and releasing carbon dioxide.
lactic acid fermentation
Glycolysis followed by the reduction of pyruvate to lactate regenerating NAD+ with no release of carbon dioxide produces latice
A complex of several membrane proteins that function in chemiosmois with adjacent electron transport chains, using the energy of a hydrogen ion concentration gradient to make ATP.
An iron containing protein that is a component of electron transport chains in the mitochondria and chloroplasts of eukaryotic cells and the plasma membranes of prokaryotic cells.
The production of ATP using energy derived from the redox reaction of an electron transport chain; the third major stage of cellular respiration.
acetyl CoA (acetyl coenzyme A)
The entry compound for the citric acid cycle in cellular respiration, formed from a fragment of pyruvate attached to a coenzyme.
krebs cycle (citric acid cycle)
A chemical cycle involving 8 steps that completes the metabolic break down of glucose molecule begin in glycolysis by oxidizing acetyl CoA to carbon dioxide; occurs within the mitochondrion; to get with pyruvate oxidation, the second major stage of cellular respiration
An energy coupling mechanism that uses energy stored in the form of a hydrogen ion gradient across a membrane to drive cellular work, such as the synthesis of ATP. Under aerobic conditions, most ATP synthesis in cells occurs by this
A series of reactions that ultimately splits glucose into pyruvate. Starting point of fermentation or cellular respiration.
A chemical reaction involving the complete or partial transfer of one or more electrons from one reactant to another.
The complete or partial addiction of electrons to a substrate involved in redox reactions.
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