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- 1 st PPI approved for PUD
- RX and OTC avail
- may take 2hrs to reach therap level
- effects last 72 hrs
- used short term (4-8wks)
- most sympt free aft 2 weeks
- most effective drug for ZE Synd
- oral only
Long term use of PPI's have shown an:
- increased risk for gastric cancer
- therapy usually limited to 2mos
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