21 terms

Rickettsial Disease

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Causative Disease
Ehrlichia spp. & Anaplasma phagocytophilum
Ehrlichia chaffeensis
causes Human Monocytic Enrlichiosis
HME
Human Monocytic Enrlichiosis
Ehrlichia ewingii
Pathogen of dogs. causes a granulocytic disease
Anaplasma phagocytophilum
causes Human Granulocytic Anaplasmosis
HGA
Human Granulocytic Anaplasmosis
Transmission
tick borne
Distribution for Human Monocytic Enrlichiosis
widely distributed in U.S. esp. SE States - few records in Europe, Asia & N. Africa
Vector for Human Monocytic Enrlichiosis
Amblyomma americanum
Amblyomma americanum
is the lone star tick
Reservoir host for Human Monocytic Enrlichiosis
white-tailed deer
1st epidemiological study for Human Monocytic Enrlichiosis
Brunswick, GA (1988)
Early symptoms of Human Monocytic Enrlichiosis
flu-like illness - fever, chills, headache, muscle aches
Late symptoms of HME
vomiting, cough, abdominal pain, lymphadenopathy, rash, confusion
Serious symptoms of HME
renal failure, vascular coagulation, seizures, coma
Leukocytopenia
Low white blood cells count
Thrombocytopenia
Low blood platelet count
Distribution of Human Granulocytic Anaplasmosis
N. America & Europe
Vectors of Human Granulocytic Anaplasmosis
Ixodes scapularis - blacklegged tick/deer tick (Eastern USA) , Ixodes pacificus - western blacklegged tick (Western USA) , Ixodes ricinus - sheep tick/ castor bean tick (Europe)
Reservoir hosts for HGA
Peromyscus spp. - white-footed mouse / cotton mouse, Neotoma spp. - woodrats
HGA treatment
doxycycline