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5 Written questions

5 Matching questions

  1. What is debranching?
  2. What is the limit dextran?
  3. What are the properties of Glycogen synthase?
  4. What enzyme catalyzes the transfer of glucose from UDP-glucose to a growing chain?
  5. What does transferase do?
  1. a Glycogen synthase catalyzes transfer of glucose from UDP-glucose to a growing chain
  2. b The 4th glucose residue from the branch glucose
  3. c A glycosyl unit from UDP glucose is transferred to the hydroxyl group at the C4 of the terminal glucose residue forming a alpha 1,4 glycosidic bond. Requires a glycogen molecule that is a minimum of 4 residues to which a glycosyl will be added
  4. d When glucose residues are removed to the "limit dextran" which is the 4th glucose residue from the branch glucose
  5. e Transferase transfers the 3 terminal glucose residues from outer branch to the center, main linear branch

5 Multiple choice questions

  1. Must be at least 4 residues away from other branches. Links are alpha 1,6 glycosidic bond
  2. Glycogen (n residues) + Pi=> glucose-1-phosphate + Glycogen (n-1 residues)
  3. Increases the number of terminal glucose residues which are site of action for glycogen phosphorylase and synthase. Branching increases rate of glycogen synthesis and degradation
  4. PPi+ H2O=> 2Pi
  5. Glycogen phosphorylase, Transferase, alpha 1,6 glucosidase, phosphoglucomutase

5 True/False questions

  1. What is the overall reaction of UDP glucose formation?Glycogen (n residues) + Pi=> glucose-1-phosphate + Glycogen (n-1 residues)

          

  2. What is glycogenin?Glycogenin is both an enzyme and its substrate consisting of two 37 kD subunits. Each subunit catalyzes addition of a glycosyl unit from UDP glucose to Tyr 194 of other subunit. Subsequently, 7 more glycosyl units are added so that 8 glycosyl units are attached to Tyr 194 for each subunit

          

  3. What are the properties of branching?A glycosyl unit from UDP glucose is transferred to the hydroxyl group at the C4 of the terminal glucose residue forming a alpha 1,4 glycosidic bond. Requires a glycogen molecule that is a minimum of 4 residues to which a glycosyl will be added

          

  4. What is glycogen?A very large, branched polymer of glucose residues. Most of the glucose residues are linked by alpha 1,4 glycosidic bonds. branches about every 10th residue are linked by alpha 1,6 glycosidic bonds

          

  5. What is Uridine Diphosphate?Uridine diphosphate is a nucleotide composed of uracil, ribose and pyrophosphate