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5 Written questions

5 Matching questions

  1. What does alpha 1,6 glucosidase do?
  2. What is phosphoglucomutase?
  3. What role does UDP-glucose play in Glycogen synthesis?
  4. What are the properties of the presumptive branch point?
  5. What converts Glucose 6 phosphate into glucose in liver?
  1. a Glycogen synthesis involves transfer of glucose from UDP-glucose to a growing chain
  2. b Alpha 1,6 glucosiase hydrolyzes the alpha 1,6 glucosidic bond to release a free glucose molecule
  3. c Glucose 6 phosphatase converts Glucose 6 phosphate into glucose for export out of the liver and transport to other tissues
  4. d Phosphoglucomutase is a phospho enzyme and converts Glucose 1 phosphate to glucose 6 phosphate for further metabolism
  5. e Must be at least 4 residues away from other branches. Links are alpha 1,6 glycosidic bond

5 Multiple choice questions

  1. Glucose-1-phosphate +UTP =>UDP-glucose + PPi
  2. Utilizes a non branched string of at least 11 glycosyl residues long. Branching enzyme transfers a string of typically 7 residues from non reducing end to presumptive branch point.
  3. When glucose residues are removed to the "limit dextran" which is the 4th glucose residue from the branch glucose
  4. Glycogen synthase catalyzes transfer of glucose from UDP-glucose to a growing chain
  5. Glycogen (n residues) + Pi=> glucose-1-phosphate + Glycogen (n-1 residues)

5 True/False questions

  1. What is glycogen?A very large, branched polymer of glucose residues. Most of the glucose residues are linked by alpha 1,4 glycosidic bonds. branches about every 10th residue are linked by alpha 1,6 glycosidic bonds

          

  2. What irreversible reaction drives the synthesis of UDP-glucose?PPi+ H2O=> 2Pi

          

  3. What is the limit dextran?A very large, branched polymer of glucose residues. Most of the glucose residues are linked by alpha 1,4 glycosidic bonds. branches about every 10th residue are linked by alpha 1,6 glycosidic bonds

          

  4. What is glycogenin?Glycogenin is both an enzyme and its substrate consisting of two 37 kD subunits. Each subunit catalyzes addition of a glycosyl unit from UDP glucose to Tyr 194 of other subunit. Subsequently, 7 more glycosyl units are added so that 8 glycosyl units are attached to Tyr 194 for each subunit

          

  5. How is UDP-glucose formed?A very large, branched polymer of glucose residues. Most of the glucose residues are linked by alpha 1,4 glycosidic bonds. branches about every 10th residue are linked by alpha 1,6 glycosidic bonds

          

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