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5 Written questions

5 Matching questions

  1. What does transferase do?
  2. What is debranching?
  3. What role does UDP-glucose play in Glycogen synthesis?
  4. What is glycogenin?
  5. What is glycogen?
  1. a Transferase transfers the 3 terminal glucose residues from outer branch to the center, main linear branch
  2. b Glycogen synthesis involves transfer of glucose from UDP-glucose to a growing chain
  3. c When glucose residues are removed to the "limit dextran" which is the 4th glucose residue from the branch glucose
  4. d Glycogenin is both an enzyme and its substrate consisting of two 37 kD subunits. Each subunit catalyzes addition of a glycosyl unit from UDP glucose to Tyr 194 of other subunit. Subsequently, 7 more glycosyl units are added so that 8 glycosyl units are attached to Tyr 194 for each subunit
  5. e A very large, branched polymer of glucose residues. Most of the glucose residues are linked by alpha 1,4 glycosidic bonds. branches about every 10th residue are linked by alpha 1,6 glycosidic bonds

5 Multiple choice questions

  1. Glycogen phosphorylase, Transferase, alpha 1,6 glucosidase, phosphoglucomutase
  2. Uridine diphosphate is a nucleotide composed of uracil, ribose and pyrophosphate
  3. Glucose 6 phosphatase converts Glucose 6 phosphate into glucose for export out of the liver and transport to other tissues
  4. Glucose-1-phosphate +UTP =>UDP-glucose + PPi
  5. Must be at least 4 residues away from other branches. Links are alpha 1,6 glycosidic bond

5 True/False questions

  1. What is the limit dextran?A very large, branched polymer of glucose residues. Most of the glucose residues are linked by alpha 1,4 glycosidic bonds. branches about every 10th residue are linked by alpha 1,6 glycosidic bonds

          

  2. What is phosphoglucomutase?Glycogenin is both an enzyme and its substrate consisting of two 37 kD subunits. Each subunit catalyzes addition of a glycosyl unit from UDP glucose to Tyr 194 of other subunit. Subsequently, 7 more glycosyl units are added so that 8 glycosyl units are attached to Tyr 194 for each subunit

          

  3. What is the overall reaction of glycogen phosphorylase activity?Glucose-1-phosphate +UTP =>UDP-glucose + PPi

          

  4. What does alpha 1,6 glucosidase do?Alpha 1,6 glucosiase hydrolyzes the alpha 1,6 glucosidic bond to release a free glucose molecule

          

  5. What enzyme catalyzes the transfer of glucose from UDP-glucose to a growing chain?Glucose-1-phosphate +UTP =>UDP-glucose + PPi

          

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