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Antiviral Medications

Terms in this set (25)

Reproductive Inhibitors
(prototype)
Acyclovir (Zovirax)
Ganciclovir (Cytovene)
Acyclovir (Zovirax)
(route)
Oral, topical
Ganciclovir (Cytovene)
(route)
Oral, IV
Acyclovir/Ganciclovir
(expected action)
Prevents the reproduction of viral DNA, which results in the interruption of cell replication
Acyclovir/Ganciclovir
(therapeutic uses)
- Herpes simplex
- Varicella-zoster
- Cytomeglovirus (CMV)
- Hepatitis
- Influenza A and B
- RSV
Acyclovir (Zovirax)
(side/adverse effects
- Phlebitis and inflammation at the site of infusion
- Nephrotoxicity
- Mild discomfort associated with oral therapy (nausea, headache, diarrhea)
Ganciclovir (Cytovene)
(side/adverse effects)
- Granulocytopenia
- Thrombocytopenia
Entry/Infusion Inhibitors
(prototype)
Enfuvirtide (Fuzeon)
Enfuvirtide (Fuzeon)
(route)
Subcutaneous
Enfuvirtide (Fuzeon)
(expected action)
Decreases and limits the spread of HIV by blocking HIV from attaching to and entering CDC4 T cell
Enfuvirtide (Fuzeon)
(therapeutic uses)
HIV
Enfuvirtide (Fuzeon)
(side/adverse effects)
- Localized reaction at injection site
- Bacterial pneumonia
- Fever, chills, rash, hypotension
Nuceloside Reverse Transcriptase Inhibitors (NRTIs)
(prototype)
Zidovudine (Retrovir)
Zidovudine (Retrovir)
(expected action)
Inhibiting DNA synthesis
Zidovudine (Retrovir)
(therapeutic uses)
HIV
Zidovudine (Retrovir)
(side/adverse effects)
- Suppresses bone marrow
- Lactic acidosis
- N/V, diarrhea
- Hepatomegaly / fatty liver
Lactic acidosis
(signs/symptoms)
- hyperventilation
- nausea
- abdominal pain
Non-Nuceloside Reverse Transcriptase Inhibitors
(prototype)
Delavirdine (Rescriptor)
Efavirenz (Sustiva)
Delavirdine/Efavirenz
(expected actions)
Acts directly on reverse transcriptase to stop HIV replication
Delavirdine/Efavirenz
(therapeutic use)
HIV
Delavirdine/Efavirenz
(side/adverse effects)
- stevens-johnson syndrome
- flu-like symptoms, headache, fatigue
Protease Inhibitors
(prototype)
Ritonavir (Norvir)
Ritonavir (Norvir)
(expected action)
Protease inhibitors act against HIV-1 and HIV-2 to alter and inactivate the virus by inhibiting enzymes needed for HIV replication
Ritonavir (Norvir)
(therapeutic uses)
HIV
Ritonavir (Norvir)
(side/adverse effects)
- Hyperglycemia
- Hypersensitivty
- N/V
- Elevated serum lipids
- Thrombocytopenia
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