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5 Written questions

4 Matching questions

  1. Key concept
  2. pathogen
  3. It is effective against a large number of organisms.
  4. Pneumococci
  1. a Pathogens are organisms that cause disease owing to their ability to divide rapidly or secrete toxins.
  2. b The value of using an antibiotic that is classified as a broad-spectrum antibiotic.
  3. c Pneumonia, otitis media, meningitis, bacteremia, endocarditis
  4. d An organism that can cause disease.

5 Multiple choice questions

  1. •Most effective against gram-positive bacteria
    •Kill bacteria by disrupting cell wall with beta-lactam ring
    •Beta-lactamase or penicillinase is enzyme allowing bacteria to be resistant
    •New penicillins are penicillinase-resistant
    -Examples: oxacillin and cloxacillin
    •Combination drugs with beta-lactamase inhibitors
    -Examples: clavulanate, sulbactam, tazobactam
    •Penicillin—Adverse Effects
    •One of safest classes of antibiotic
    •Allergy most common adverse effect
    •If client allergic to penicillin, avoid cephalosporins
    -Possibility of cross-hypersensitivity
    •Other adverse effects
    -Skin rash; decreased RBC, WBC, or platelet counts
  2. Lyme disease
  3. Pharyngitis, pneumonia, skin infections, speticemia, endocarditis
  4. Bacteria that grow best without oxygen.
  5. effective for MRSA infections
    •Adverse effects: ototoxicity, nephrotoxicity, red man syndrome

5 True/False questions

  1. Key conceptResistance has limited the usefulness of once widely prescribed sulfonamides to urinary tract infections and a few other specific infections.


  2. bacteriocidalMedications that treat by killing bacteria.


  3. superinfectionsA common side effect of anti-infective therapy which occur when microorganisms normally present in the body are destroyed.


  4. Key conceptPrototype drug: tetracycline HCL (Achromycin, others)
    Mechanism of action: effective against broad range of gram-positive and -negative organisms
    Primary use: chlamydiae, rickettsiae, and mycoplasma
    Adverse effects: superinfections, nausea, vomiting, epigastric burning, diarrhea, discoloration of teeth, photosensitivity


  5. Key conceptPenicillins, which kill bacteria by disrupting the cell wall, are most effective against gram-positive bacteria. Allergies occur most frequently with the penicillins.


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