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5 Written questions

5 Matching questions

  1. Define hepatotoxicity. What labs are involved?
  2. Digoxin (Lanoxin)
  3. Mannitol (osmitrol)
  4. Define teratogen
  5. Fluticasone Propionate (Flonase)
  1. a indications: dysrhythmias, <3 failure,
    AE: dysrhythmias, hypokalemia, toxicity, n/v, halos,
    *pulse must be at least 60 bpm
    *therapeutic leve = 0.5-0.8
  2. b *inhaled glucocorticoid
    indications: long term asthma, nasal congestion, seasonal and perennial rhinitis
    AE: adrenal suppression and bone loss, oral & pharyngeal candidiasis, disphonia (hoarseness)
  3. c a- toxicity in the liver
    b-check the AST (asparte aminotransferase) and ALT (alanine aminotransferase) labs (normally low)
    c- s/s jaundice, dark urine, light colored stools, n/v, malaise, abd discomfort, and decreased appetite
  4. d an agent or factor that causes a malformation of an embryo.
    1- drug must cause a characteristic set of malformations
    2-must act only during a specific window of vulnerability (wks 4-7 of gestation)
    3-incidence of malformations should increase with increasing dosage and duration of exposure
  5. e indications: prophylaxis of renal failure, reduction of intracranial/intraocular pressure
    - give IV
    AE: edema, HA, n/v, F&E imbalance
    - d/c if signs of pulmonary congestion, chronic heart failure, or renal failure develop

5 Multiple choice questions

  1. indications: atypical depression, bulimia, OCD, and can reduce panic attacks
    - cause direct CNS stimulation
    AE: anxiety, insomnia, aggitation, hypomania, and mania
    Foods that are low in tyramine are safe: most veggies (not avocados), most fruits (no figs or bananas), fresh meat, milk, yogurt, cottage cheese, cream cheese and baked good that contain yeast are safe to eat
    *last resort drug
  2. indications: TB
    - always used w/ other TB meds
    AE: red orange discoloration of secretions, hepatotoxicity, hepatitis
  3. indications: duodenal ulcers, gastric ulcers, erosive esophagitis, & GERD. long term treatment of Zollinger Ellison Syndrome
    AE: HA, diarrhea, n/v, gastric ca, hip fx
    MoA: a prodrug, converted to active form inside parietal cells of the stomach, acive form then causes irreversible inhibition of H+, K+-ATPase (proton pump) the enzyme that generates gastric acid
  4. - incidence and severity of infections are increased
    - no fresh fruit or veggies due to bacteria
    - normal neutrophil count is 2500-7000 cells/mm3 if it drops below 500 cells/mm3 chemo should be withheld
    - must be in isolation room
    - monitor for fever!
  5. indications: seasonal allergic rhinitis, cold symptoms, allergic reactions, motion sickness, sleep aid (doesn't reduce nasal congestion)
    AE: anticholinergic effects (dry mouth/nose/eyes), urinary retention, constipation, and drowsiness

5 True/False questions

  1. Zidovudine (Retrovir)indications: dysrhythmias, <3 failure,
    AE: dysrhythmias, hypokalemia, toxicity, n/v, halos,
    *pulse must be at least 60 bpm
    *therapeutic leve = 0.5-0.8


  2. Sulfonamidesindications: UTIs
    AE: hypersensitivity, photosensitivity, Steven's Johnson Syndrome


  3. Dronabinol and Marinol* additional anitemetics
    indications: CINV, and increase appetites in clients w/ AIDS
    AE: potential for disocation, disphoria, hypotension, tachycardia, avoid pts w/ mental disorders


  4. Define physical dependence-has only moderate intrinsic activity
    -the maximal effect that a partial agonist can produce is lower than that of a full agonist
    - can act as agonists or antagonists


  5. Antitussives*codeine
    indications: decrease frequency, intensity of cough. Suppresses the cough reflex directly at the cough center in the medulla
    AE: suppress respirations, cause drowsiness, dizziness, HA, blurred vision, upset stomach, nausea, constipation, dry mouth/nose/throat