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5 Written questions

5 Matching questions

  1. Warfarin (coumadin)
  2. Vincristine (Oncovin)
  3. Epinephrine (adrenaline, epi-pen)
  4. Neuromuscular Blockers (succinylchoine)
  5. Acetaminophen (Tylenol)
  1. a indications: mainly - anaphalactic shock, also - delay absorption of local anesthetics, overcome AV heart block, cardiac arrest, asthma
    - catacholamine ( not by mouth, given parentarally)
    - can't cross BBB
    AE: tachycardia, HTN crisis, angina, hyperglycemia, necrosis following extravasations (only IV)
  2. b indications: prevention of venous thrombosis
    AE: hemorrhage, harmful during pregnancy and lactation
    lab values: INR 2-3, PT INR 1.5-2
    Antidote: Vitamin K
  3. c indications: flaccid paralysis, procedures, endoscopy
    AE: apnea, hypotension, malignant hyperthermia, hyperkalemia w/ cardiac arrest, muscle pain,
    * contraindicated for pt with Myasthenia Gravis
    *does not block pt's conscious- can feel pain and hear
    antidote for mailgnant hyperthermia = dantrolene
  4. d indications: bone marrow sparing (chemo), hodgkin's and nonhodgkin's lymphoma, acute lymphocytic leukemia, wilm's tumor, rhabdomyosarcoma, kaposi's syndrome, breast ca, bladder ca
    AE: peripheral neuropathy
    route: IV
  5. e indications: mild pain, fever
    AE: rare, w/ acute toxicity liver damage and death
    liver damage can be minimized w/ mucomyst/acedote
    - don't drink alcohol
    - not an anti-inflammatory

5 Multiple choice questions

  1. indications: hypothyroidism, maintains thyroid levels after surgery
    AE: rare, w/ acute OD thyrotoxicosis can occur s/s tachycardia, angina, tremor, nervousness, insomnia, hyperthermia, heat intolerance, & sweating
  2. cause: clindamycin, amoxicillin, ampicillin, cephalexin
    bacterial infection - contact, hand sanitizer doesn't kill it!
    treatments: metronidiazole (Flagyl) or vanco
  3. refrigerated until expiration date
    if not refrigerated good for a month
    do not freeze
    keep out of sunlight and extreme heat
  4. hyperglycemia, hypoglycemia, and ketoacidosis
  5. indications: pulmonary edema (CHF), edema, HTN, renal impairment
    AE: hyponatremia, hypochloremia, dehydration, hypotension, hypokalemia, ototoxicity

5 True/False questions

  1. Define toxicityan adverse drug reaction caused by excessive dosing. when way too much medication is in the blood stream from either an overdose or the drug being unable to be metabolized or excreted


  2. Bulk forming LaxativesSodium Phosphate (Fleet)
    - osmotic laxative that draws water into the feces. In high doses it can produce a watery stool in 6-12 hours and in low doses a semi-fluid stool in 6-12 hours
    *used b4 surgery
    AE: loss of h2o, sodium absorption can cause fluid retention which can exacerbate HF, HTN, and edema, can also cause renal failure in pts w/ kidney disease and those taking drugs that alter renal function (diuretics, ACE inhibitors, ARBs)
    Docusate Sodium (Colace)
    -surfactant laxative, softens stool by penetration of water.
    -take with full glass of h2o
    - produces a soft stool in 1-3 days
    - same AE as above


  3. Define therapeutic indexthe movement of drugs and their metabolites out of the body via urine, bile, sweat, saliva, breast milk, and expired air


  4. TCAs (amitriptyline/Elavil)a decreasing response to repetitive drug doses


  5. NSAIDs (buprofen)indications: inflammation, mild to moderate pain, fever reduction, dysmenorrhea
    AE: mild GI reactions, ulceration, bleeding, increase for MI and stroke, renal impairment, hypersensitivity, reye's syndrome, conjunctivitis, nose bleed, steven's johnson syndrome