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5 Written questions

5 Matching questions

  1. Define absorption
  2. Propylthiouracil (PTU)
  3. Define metabolism
  4. Estrogen Therapy
  5. Caffeine
  1. a indications: hypERthyroidism
    AE: agranulocytosis, sore throat, fever, hypothyroidism, RASH, nausea, arthralgia, HA, dizziness, paresthesias, elevation of liver function tests
    * crosses placenta and breast milk
  2. b indications: female hypogonadism, acne, post-menopausal hormonal levels
    AE: endometrial hyperplasia and carcinoma, breast ca, ovarian ca, nausea, cardiovascular effects (PE, VTE, and stroke)
  3. c indications: decrease drowsiness, fatigue, peripheral vasodilation, CNS vasoconstriction, relaxation of bronchi, neonatal apnea
    AE: convulsions, tinnitus, flashing lights, palpitations, dizziness, diuresis, tachycardia, respiratory stimulation
  4. d aka biotransformation
    enzymatically mediated alteration of drug structure
  5. e the movement of a drug from its sight of administration into the blood. The rate of absorption determines how soon effects will begin. The amount of absorption helps determine how intense effects will be.

5 Multiple choice questions

  1. *codeine
    indications: decrease frequency, intensity of cough. Suppresses the cough reflex directly at the cough center in the medulla
    AE: suppress respirations, cause drowsiness, dizziness, HA, blurred vision, upset stomach, nausea, constipation, dry mouth/nose/throat
  2. fast acting due to skipping the absorption period
    control of drug levels in blood
    use of large fluid volumes
    use of irritant drugs
    - can't reverse w/o antidote, expensive
  3. indications: used as an anticoagulant, prophylaxis of DVT
    AE: hemorrhage, immune mediated thrombocytopenia, and severe neurologic injury
    Labs: none needed
  4. indications: latent and active TB
    AE: peripheral neuropathy (tingling, numbness, pain in hands & feet, burning) <- give B6 for this
    hepatotoxicity
  5. indications: antidepressant for depression and bipolar disorder
    AE: orthostatic hypotension, anticholinergric effects (dry mouth, constipation, dry eyes), diaphoresis, sedation, cardiac toxicity, seizure, hypomania, suicide risk
    drug interactions: MAOIs, sympathomymetics, anticholinergics, CNS depressants
    *effects begin in 1-2 months

5 True/False questions

  1. Define and describe allergic reaction / hypersensitivitysubQ - (abd for most consistency)
    inhalation
    subQ infusion (delivers basal infusion and bolus at mealtime
    IV (regular)

          

  2. What is the goal of cancer pain management?- a blood test done to check long-term blood sugar twice a tear over 3 months in diabetic pts.
    - fasting is not necessary
    - ideal value is <7% for diabetic, <6% for normal

          

  3. Sodium Containing LaxativesSodium Phosphate (Fleet)
    - osmotic laxative that draws water into the feces. In high doses it can produce a watery stool in 6-12 hours and in low doses a semi-fluid stool in 6-12 hours
    *used b4 surgery
    AE: loss of h2o, sodium absorption can cause fluid retention which can exacerbate HF, HTN, and edema, can also cause renal failure in pts w/ kidney disease and those taking drugs that alter renal function (diuretics, ACE inhibitors, ARBs)
    Docusate Sodium (Colace)
    -surfactant laxative, softens stool by penetration of water.
    -take with full glass of h2o
    - produces a soft stool in 1-3 days
    - same AE as above

          

  4. What is schizophrenia?a chronic psychotic illness characterized by disordered thinking and reduced ability to comprehend reality
    + symptoms: exaggeration or distortion of normal functioning, hallucinations, delusions, agitation, tension, and paranoia. respond to 1st and 2nd gen
    - symptoms: loss or diminution of normal function, lack of motivation, poverty of speech, blunted effect, poor self care, social withdrawal. 1nd gen are better treatment for - symptoms

          

  5. Routes of administration for Insulin-erosion of gastric wall due to long-term aspirin use
    -increased secretion of gastric acid and pepsin
    -decreased production of cytoprotective mucus and bicarbonate
    -decreased submucosal blood flow
    -infection of H. pylori
    -drugs that cause gastric ulcers = NSAIDs aspirin