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5 Written questions

5 Matching questions

  1. Define therapeutic index
  2. Aminoglycosides (gentamycin, garamycin)
  3. ACE Inhibitors (captopril/captopen)
  4. Short term complications of DM
  5. Lovenox (low molecular weight heparin)
  1. a hyperglycemia, hypoglycemia, and ketoacidosis
  2. b indications: used as an anticoagulant, prophylaxis of DVT
    AE: hemorrhage, immune mediated thrombocytopenia, and severe neurologic injury
    Labs: none needed
  3. c indications: HTN, <3 failure, LVD after MI, diabetic neuropathy, decrease risk of cardiovascular mortality, reduces cardiac afterload, increases CO, increases regional blood flow, decreases pulmonary congestion and peripheral edema, increases renal blood flow, increases excretion of Na and H2O, decreases venous return to the <3
    AE: cough, angioedema, 1st dose orthostatic hypotension, hyperkalemia, fetal injury
    * tell pt to change positions slowly, let feet dangle before getting out of bed
  4. d indications: aerobic gram -, serious infections, E. Coli, Klebsiella, Serratia and proteus mirabilis
    AE: ototoxicity, nephrotoxicity, neuromuscular blockade, & hypersensitivity reactions
  5. e a measure of a drug's safety.
    ratio of a drugs LD (lethal dose) to its ED (effective dose)
    A large (or high) therapeutic index indicated a realitively safe drug, conversely, a small (or low) therapeutic index indicates that a drug is relatively unsafe

5 Multiple choice questions

  1. macrovascular damage
    heart disease
    hypertension
    stroke
    hyperglycemia
    altered lipid metabolism
    retinopathy
    nephropathy
    neuropathy
    gastroparesis
    amputations
    erectile dysfunction
  2. 1. inject air into NPH (cloudy)
    2. inject air into regular (clear)
    3. withdrawal regular
    4. withdrawal NPH
    Clear before cloudy!
  3. indications: antifungal agent, mycoses
    AE: nephrotoxicity (monitor urine output), infusion reactions (fever, chills, nausea, HA), hypokalemia, bone marrow suppression
  4. -has only moderate intrinsic activity
    -the maximal effect that a partial agonist can produce is lower than that of a full agonist
    - can act as agonists or antagonists
  5. - to minimize the risk of injury, IV admin should be performed only into a vein w/ good flow.
    - Sites of previous irradiation should be avoided
    - If extravasation occurs, infusion d/c immediately
    - extreme caution should be employed

5 True/False questions

  1. Rifampin (rifadin)indications: TB
    - always used w/ other TB meds
    AE: red orange discoloration of secretions, hepatotoxicity, hepatitis

          

  2. Antitussives*codeine
    indications: decrease frequency, intensity of cough. Suppresses the cough reflex directly at the cough center in the medulla
    AE: suppress respirations, cause drowsiness, dizziness, HA, blurred vision, upset stomach, nausea, constipation, dry mouth/nose/throat

          

  3. What is tolerance?- a blood test done to check long-term blood sugar twice a tear over 3 months in diabetic pts.
    - fasting is not necessary
    - ideal value is <7% for diabetic, <6% for normal

          

  4. Levothyroxine (Synthroid)indications: hypothyroidism, maintains thyroid levels after surgery
    AE: rare, w/ acute OD thyrotoxicosis can occur s/s tachycardia, angina, tremor, nervousness, insomnia, hyperthermia, heat intolerance, & sweating

          

  5. Define teratogenthe movement of drugs and their metabolites out of the body via urine, bile, sweat, saliva, breast milk, and expired air