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16 terms

Diabetes Mellitus

STUDY
PLAY
Type 1
-pancreas no longer produces insulin
-juvenile onset, insulin dependent
Type 2
-pancreas produces insulin, but body tissue resistant to it
-adult onset, non-insulin dependent
Galega Officinalis
cn: goat's rue
geo: europe to iran
ethno: type 2
active: galegine, phenformin
chem deriv: phenformin--> metformin (glucophage)
mech: reduction of insulin resistance
modern use: type 2
Larrea Divaricata
cn: creosote bush
geo: USA & NW Mexico
ethno: type 2, kidney disease
active: masoprocol
Momordica Charantia
-bitter melon, bitter cucumber
-tx type 2
Cinnamomun Verum
cinnamon
asia
Hypericum perforatum
-st. john's wort
-eurasia
-orally for depression, type 2; topically for wounds

active: hyperforin
reduces insulin resistance
Camellia sinensis
-tea
-asia
coffea arabica
coffee
NE Africa
Vernonia amygdala
bitter leaf
W. Africa
Opuntia basileris
-prickly pear
-mexico, SW USA
-orally by indigenious groupt to type 2
-reduces sugar absorption by intestine
Gymnema sylvestre
-Gudmar
-India
-active: gymnemic acid
-mech: when leaves are chewed, ability of the taste buds to perceive sweetness is diminished which reduces appetite and treats type 2
Synsepalum Dulcificum
-cn: agbayun & miracle fruit
-geo: west africa
-active: miraculin=glycoprotein with trailing carb chain

-mech: chewing on fruit increases perceived sweetness of food and sour foods to taste very sweet; may work by distorting shape of sweetness receptors so they become responsive to acids instead of sugar; lasts 15-60 min

-therapeutic: ability of fruit to turn non sweet foods into sweet foods w/o caloric penalty
Thaumatoccus daniellii
geo: west africa
active: thaumatic (intensely sweet protein)
thera: ability of fruit to turn non-sweet foods into sweet foods
Stevia Rebaudiana
cn: sweet leaf, sugar leaf
geo: SA
active: steviol glycoside
thera: ability of fruit to turn non-sweet foods into sweet foods
Morinda Citrifola
cn: noni, nono
geo: SE Asia
ethnobotanical use: fruit used to treat type 2, arthritis, applied topically to treat skin boils